CLINICAL STAGE II HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Clinical trials for CLINICAL STAGE II HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8 explained in plain language.
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New combo therapy aims to boost survival in head and neck cancer
Disease control Recruiting nowThis phase II trial tests whether adding chemotherapy or chemo-immunotherapy before standard salvage surgery helps patients with recurrent or persistent head and neck cancer. About 180 participants with PD-L1 positive tumors will receive either carboplatin and paclitaxel, or thos…
Matched conditions: CLINICAL STAGE II HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 23, 2026 18:31 UTC
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Blood test could help throat cancer patients get less radiation
Disease control Recruiting nowThis phase II trial tests whether a blood test that detects HPV DNA can help doctors decide the right amount of radiation for people with HPV-positive throat cancer. About 455 participants will either have surgery or receive standard chemotherapy plus radiation, but the radiation…
Matched conditions: CLINICAL STAGE II HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 23, 2026 11:56 UTC
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Could less radiation be better? new trial aims to cut side effects in HPV throat cancer
Disease control Recruiting nowThis study is for people with early-stage HPV-related throat cancer. It tests whether giving a lower dose of radiation to the lymph nodes in the neck that are not directly affected by cancer can reduce side effects while still keeping the cancer under control. About 100 participa…
Matched conditions: CLINICAL STAGE II HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated Jun 18, 2026 11:50 UTC
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Blood test may allow safer, Lower-Dose radiation for throat cancer patients
Disease control Recruiting nowThis study tests whether a blood test that detects HPV DNA can guide doctors to safely use a lower dose of radiation for people with HPV-related throat cancer. About 45 adults with early-stage HPV-positive oropharyngeal cancer will receive radiation and chemotherapy. The goal is …
Matched conditions: CLINICAL STAGE II HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 08, 2026 13:11 UTC
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New drug aims to prevent painful mouth sores in head and neck cancer treatment
Symptom relief Recruiting nowThis study tests whether adding BMX-001 to standard care can reduce severe mouth sores caused by chemoradiation in head and neck cancer patients. About 98 participants will receive either BMX-001 or a placebo alongside usual mouth rinses and pain medications. The goal is to impro…
Matched conditions: CLINICAL STAGE II HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated Jun 15, 2026 18:57 UTC
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Can blood tests predict who will do their swallowing exercises?
Knowledge-focused Recruiting nowThis study looks at why people with head and neck cancer follow (or don't follow) swallowing exercises after radiation. Researchers will use blood tests and questionnaires to see if immune system proteins or feelings about the disease affect exercise habits. The goal is to find w…
Matched conditions: CLINICAL STAGE II HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:08 UTC
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New imaging study aims to spot radiation damage to neck arteries
Knowledge-focused Recruiting nowThis study looks at how radiation therapy for head and neck cancers affects the blood vessels in the neck. Researchers will use two types of PET/CT scans to compare images taken before and after treatment. The goal is to better understand and detect radiation-related vascular dam…
Matched conditions: CLINICAL STAGE II HPV-MEDIATED (P16-POSITIVE) OROPHARYNGEAL CARCINOMA AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:07 UTC