CLEFT PALATE
Clinical trials for CLEFT PALATE explained in plain language.
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Fat graft patch shows promise for closing cleft palate holes
Disease control CompletedThis study tested a new surgical technique for repairing a common complication after cleft palate surgery: a small hole (fistula) in the roof of the mouth. In 36 patients, surgeons added a free fat graft from the cheek between the two standard closure layers. The goal was to see …
Matched conditions: CLEFT PALATE
Phase: NA • Sponsor: Tanta University • Aim: Disease control
Last updated May 26, 2026 06:25 UTC
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New expander device shows promise for cleft patients
Disease control CompletedThis study tested a new device called the Leaf Self Expander to widen the upper jaw in 20 children with cleft lip and palate. The goal was to see if it works better than the standard expander. Researchers used 3D scans to measure changes in bone and tooth position. The study is c…
Matched conditions: CLEFT PALATE
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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New study tests drug to calm kids after cleft palate surgery
Symptom relief CompletedThis study tested whether a single dose of dexmedetomidine, given during surgery, can prevent agitation in children aged 1-7 years after cleft palate repair. Sixty children were randomly assigned to receive either the drug or a placebo (saline). The main goal was to measure emerg…
Matched conditions: CLEFT PALATE
Phase: PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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Cleft Surgery's hidden impact on palate blood flow revealed
Knowledge-focused CompletedThis study looked at how routine cleft repair surgery changes blood flow in the roof of the mouth. Researchers used a non-invasive probe to measure oxygen levels in the tissue before and after surgery in 77 patients. The goal was to understand how surgery affects healing and to p…
Matched conditions: CLEFT PALATE
Sponsor: University Hospital, Basel, Switzerland • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC