CIRCULATING TUMOR DNA

This study tests whether a blood test that detects tiny bits of tumor DNA can identify lung cancer patients whose cancer might return after surgery. Those with positive results receive extra treatment (chemo plus immunotherapy) to try to eliminate any remaining cancer cells. The …

This study tests whether two drugs, sacituzumab govitecan and atezolizumab, can clear leftover cancer cells in the breast or lymph nodes of people with triple negative breast cancer. About 40 participants who still have cancer after standard chemotherapy will receive the combinat…

This study looks at whether DNA from blood, sputum, lung fluid, and breath can help find genetic changes in non-small cell lung cancer. About 210 people having surgery to remove their lung cancer will provide samples before and after surgery. Researchers will check if these sampl…

This study looks at using a blood test that detects tiny bits of tumor DNA (ctDNA) to guide chemotherapy decisions in people with stage II colon cancer. About 1,320 participants will be randomly assigned to either have their treatment based on the blood test results or receive st…

This study looks at new ways to detect if vulva cancer has come back after treatment. Researchers will ask 295 women to fill out surveys every four months and give blood samples to look for cancer DNA. They will compare results with a group of 1000 women treated in the past. The …

This study is for people with a first-time diagnosis of high-grade serous ovarian cancer. Researchers will collect blood samples before surgery, after chemotherapy, and during maintenance therapy to look for circulating tumor DNA (ctDNA). The goal is to see if ctDNA can predict h…

This study is collecting blood samples from 1,000 people with digestive, gynecologic, or breast cancer to study tiny bits of tumor DNA and particles called exosomes floating in the blood. Researchers want to see if these markers can help predict how the cancer will behave, whethe…