CHRONIC PAIN SYNDROME

This early-stage study tests whether adding lacosamide, a seizure medication, to standard opioid therapy is safe and tolerable for people with chronic pancreatitis and ongoing abdominal pain. About 24 adults who have been on opioids for at least 4 weeks will take lacosamide for 7…

This study tests whether a spinal cord stimulator can reduce leg pain and improve quality of life in people with type 2 diabetes, painful nerve damage, and peripheral artery disease. Fifteen adults who already have a spinal cord stimulator will receive two weeks of active stimula…

This study is testing whether a mind-body therapy program can reduce disability and pain in people with chronic back pain. About 150 adults aged 18 to 67 with persistent back pain will be randomly assigned to the mind-body program, a different mind-body approach, or usual care. R…

This study tests whether adding shiatsu therapy to usual medical care can improve quality of life for children and teens (ages 10-18) with chronic pain that is not caused by inflammation. About 40 participants will receive a 30-minute shiatsu session once a week for six weeks and…

This pilot study tests a mind-body intervention for adults with chronic upper extremity pain from repetitive stress injury. Researchers want to see if the program improves arm, shoulder, and hand function, and reduces pain and anxiety. The study enrolls 40 participants who have h…

This study looks at how teenagers with chronic pain notice and understand signals from their own bodies, like heartbeat or tension. Researchers want to see if occupational therapy changes this body awareness and improves daily function. About 49 teens aged 11 to 21 will fill out …

This study uses a smartphone app called SOMA to track daily mood, pain, and activity in 800 people with acute or chronic pain over four months. The goal is to see if daily changes in these factors can predict whether pain becomes long-term or flares up. A smaller group will also …

This study aims to find out how many people with fibromyalgia have damage to their small nerve fibers, compared to people with other types of chronic pain and healthy volunteers. Researchers will use skin biopsies and other tests to check for nerve problems. The goal is to better…