CHRONIC MYELOID LEUKEMIA
Clinical trials for CHRONIC MYELOID LEUKEMIA explained in plain language.
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Leukemia drug holiday: many patients stay in remission after stopping nilotinib
Disease control CompletedThis study looked at whether people with chronic myeloid leukemia (CML) could safely stop taking the drug nilotinib (Tasigna) if their cancer was already deeply suppressed. Participants had been on nilotinib for at least 2 years and had very low levels of leukemia cells. The main…
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 07:42 UTC
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Boosting transplants with natural killers: new combo aims to stop blood cancer return
Disease control CompletedThis phase 2 trial tested whether adding ready-made donor natural killer (NK) cells to a standard stem cell transplant could safely reduce the chance of cancer coming back in people with high-risk myeloid cancers like AML, MDS, and CML. Twenty-four patients received the combinati…
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 07:41 UTC
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Can CML patients finally take a drug holiday? new study explores stopping treatment
Disease control CompletedThis study looked at whether people with chronic myeloid leukemia (CML) who have been on the drug nilotinib for at least 3 years can safely reduce their dose or stop treatment entirely. It involved 124 adults and tested two approaches: first, cutting the nilotinib dose in half fo…
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 07:24 UTC
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New combo therapy shows promise for leukemia patients
Disease control CompletedThis study tested whether adding pegylated interferon to the standard drug nilotinib helps people with newly diagnosed chronic myeloid leukemia (CML) achieve a deeper molecular response. About 200 adults under 65 took either nilotinib alone or nilotinib plus the added drug for up…
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE3 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated May 26, 2026 07:23 UTC
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Healthy men swallow radioactive drug to map its journey – no treatment intended
Knowledge-focused CompletedThis study looked at how the body absorbs, breaks down, and gets rid of a drug called TGRX-678, which is used for chronic myeloid leukemia. Six healthy men took a single radioactive dose so researchers could track it in blood, urine, and stool. The goal was not to treat anyone, b…
Matched conditions: CHRONIC MYELOID LEUKEMIA
Phase: PHASE1 • Sponsor: Shenzhen TargetRx Co., Ltd. • Aim: Knowledge-focused
Last updated May 26, 2026 07:26 UTC