CHRONIC GRANULOMATOUS DISEASE
Clinical trials for CHRONIC GRANULOMATOUS DISEASE explained in plain language.
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Partial match transplant could cure rare immune disease
⭐️ CURE ⭐️ OngoingThis study tests a new approach to bone marrow transplant for people with chronic granulomatous disease (CGD) who don't have a perfectly matched donor. The goal is to see if using a partially matched relative as a donor, along with special drugs and radiation, can safely cure the…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: EARLY_PHASE1 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: ⭐️ CURE ⭐️
Last updated May 26, 2026 07:44 UTC
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New gene therapy could help people with rare immune disease fight infections
Disease control ENROLLING_BY_INVITATIONThis study tests a new gene therapy for people with a rare genetic disorder called chronic granulomatous disease (CGD), which makes them prone to severe infections. The treatment involves taking the patient's own stem cells, adding a missing gene in the lab, and returning them to…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated May 26, 2026 07:45 UTC
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Milder stem cell transplant offers hope for kids with rare immune diseases
Disease control OngoingThis study tests a less intense stem cell transplant for children and young adults up to age 28 with various immune system disorders. The goal is to see if a milder pre-transplant treatment can help donor cells take hold with fewer serious side effects. The study tracks engraftme…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 26, 2026 07:42 UTC
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Stem cell transplant offers new hope for kids with rare immune diseases
Disease control OngoingThis study tests a donor stem cell transplant to treat severe immune system problems in 57 people. The goal is to help the body make healthy blood cells and fight infections. Patients must have a specific immune disorder and meet health criteria to join.
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated May 26, 2026 07:25 UTC
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Groundbreaking gene therapy aims to fix immune system in rare disease
Disease control ENROLLING_BY_INVITATIONThis study tests a new gene therapy called PM359 for people with a rare immune disorder called chronic granulomatous disease (CGD). The therapy takes the patient's own blood stem cells, fixes a specific gene mutation using a precise editing tool called prime editing, and then ret…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Prime Medicine, Inc. • Aim: Disease control
Last updated May 26, 2026 07:23 UTC
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Gene therapy trial for rare immune disease withdrawn before start
Disease control TerminatedThis study aimed to test a gene therapy for X-linked chronic granulomatous disease (CGD), a rare immune disorder that makes patients prone to severe infections. The treatment involved taking the patient's own blood stem cells, adding a corrected gene, and returning them to the bo…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: Helixmith Co., Ltd. • Aim: Disease control
Last updated May 18, 2026 12:04 UTC