CHRONIC GRANULOMATOUS DISEASE
Clinical trials for CHRONIC GRANULOMATOUS DISEASE explained in plain language.
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New hope for rare immune disease: tofacitinib tested in small trial
Disease control CompletedThis study tested the safety of the drug tofacitinib in 10 adults with chronic granulomatous disease (CGD) who had ongoing inflammation in the gut, skin, or lungs. Participants took tofacitinib pills for 3 months and were monitored for side effects and infections. The goal was to…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated May 26, 2026 08:35 UTC
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Liquid diet shows promise for gut troubles in rare immune disease
Disease control CompletedThis study looked at whether a special liquid diet (elemental diet) could improve gut symptoms in people with chronic granulomatous disease (CGD) and inflammatory bowel disease (IBD). Three participants aged 8-65 stayed in the hospital for up to 2 weeks and followed the diet for …
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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New tool helps young cancer patients voice their care wishes
Knowledge-focused CompletedThis study tested a document called Voicing My CHOiCES, designed to help young adults (ages 18-39) with cancer or other chronic illnesses talk about their end-of-life care preferences. Participants filled out questionnaires and reviewed the document with a healthcare provider. Th…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 19, 2026 12:01 UTC
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Scientists compare transplant vs. standard care for rare immune disease
Knowledge-focused CompletedThis study looked back at medical records of 137 people with chronic granulomatous disease (CGD), a rare immune disorder. Researchers compared those who had a stem cell transplant with those who received standard care to see who lived longer and had fewer infections. The goal was…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC
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Scientists probe genetic roots of stubborn lung infections
Knowledge-focused CompletedThis study looked at people with diseases that make it hard to clear mucus from the lungs, like cystic fibrosis and primary ciliary dyskinesia. Researchers did tests and genetic analysis to better understand why these patients get repeated lung infections and to find the genes re…
Matched conditions: CHRONIC GRANULOMATOUS DISEASE
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated May 13, 2026 16:00 UTC