Central nervous system diseases
Clinical trials for Central nervous system diseases explained in plain language.
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Stroke-Clot zapper: new device could save brains within 24 hours
Disease control Not yet recruitingThis trial tests a new device called Supernova that removes blood clots from large brain arteries in people having a stroke. The goal is to restore blood flow within 24 hours of symptoms starting. The study will include 3,000 participants and measure how well the device works and…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Sponsor: Gravity Medical Technology, INC • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Can tiny tablets replace protein powder for kids with PKU?
Symptom relief Not yet recruitingThis trial tests whether XPhe Piccos, a slow-release protein substitute in tiny tablets without phenylalanine, is acceptable and well-tolerated in children aged 3 and older with phenylketonuria (PKU) or hyperphenylalaninemia. Participants replace some or all of their usual protei…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Sponsor: metaX Institut fuer Diatetik GmbH • Aim: Symptom relief
Last updated Sep 05, 2026 00:00 UTC
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Spinal fluid biobank aims to unlock secrets of rare childhood brain disorders
Knowledge-focused Not yet recruitingThis study will collect and analyze cerebrospinal fluid from 1,000 children with various neurological conditions, such as traumatic brain injury or hydrocephalus. Researchers will look for protein markers that could help diagnose and track these diseases more accurately. The goal…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Sponsor: Imagine Institute • Aim: Knowledge-focused
Last updated Sep 11, 2026 00:00 UTC
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Headache trigger test: could amylin be the culprit?
Knowledge-focused Not yet recruitingThis study gives people with persistent post-traumatic headache a hormone called amylin (or a placebo) to see if it triggers migraine-like headaches. The goal is to understand why headaches continue after a mild brain injury. Only 21 adults will take part, and the results may hel…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Scientists investigate if amylin analogue sparks migraines
Knowledge-focused Not yet recruitingThis study looks at whether pramlintide, a drug similar to the hormone amylin, can cause migraine attacks in people who get migraines without aura. Researchers will give 21 participants either pramlintide or a placebo and watch for headaches over 12 hours. The goal is to understa…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC