CARCINOID TUMOR

This study tests a different way of taking the drug cabozantinib to see if it causes fewer side effects while still controlling cancer growth. It includes adults with advanced kidney cancer or neuroendocrine tumors. The goal is to find a dose schedule that patients can tolerate b…

This study tests a new drug called RYZ101 in people with advanced neuroendocrine tumors of the gut or pancreas that cannot be removed by surgery and have grown after prior treatment with a type of radiation therapy (177Lu). The trial has two parts: first, finding the best dose, t…

This study tests a combination of two immunotherapy drugs (domvanalimab and zimberelimab) in people with five types of rare advanced cancers that have stopped responding to standard treatment. The goal is to see if this treatment can control the cancer better than older therapies…

This study tests an experimental drug called paltusotine in 141 adults with carcinoid syndrome caused by neuroendocrine tumors. The goal is to see if it reduces daily flushing and diarrhea better than a placebo. Participants take the drug or placebo for 12 weeks and record their …

This early-stage study tests a new radioactive drug called RYZ401 in people with neuroendocrine tumors and other solid tumors that have a specific protein on their surface. The main goals are to find the safest dose and schedule, and to see if the drug can shrink tumors. About 10…

This study tests whether using virtual reality (VR) can reduce severe belly pain and improve daily life in people with digestive tract cancers. 360 participants will be randomly assigned to one of three groups: skills-based VR, distraction VR, or a sham VR. The goal is to see if …

This study is a registry that collects information from 3,750 adults with lung cancer across 21 hospitals in Algeria. Researchers will track patient details, tumor types, treatments, and outcomes over time. The goal is to understand how lung cancer is diagnosed and managed in rea…