CANCER OF HEAD AND NECK
Clinical trials for CANCER OF HEAD AND NECK explained in plain language.
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New chemo cocktail shows promise for tough head and neck cancers
Disease control CompletedThis study tested a combination of three chemotherapy drugs (cisplatin, 5-fluorouracil, and docetaxel) at lower, adjusted doses in 105 people with advanced head and neck cancer that could not be surgically removed. The goal was to see if the treatment could shrink tumors effectiv…
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Groupe Oncologie Radiotherapie Tete et Cou • Aim: Disease control
Last updated May 26, 2026 12:00 UTC
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Could a common ED drug boost cancer immunotherapy?
Disease control CompletedThis study tested whether adding tadalafil (a drug often used for erectile dysfunction) to pembrolizumab (an immunotherapy) could help control advanced head and neck cancer. Seven adults with recurrent or metastatic disease participated. The goal was to check safety and see if th…
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated May 26, 2026 11:59 UTC
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Immunotherapy shows promise in shrinking head and neck tumors before surgery
Disease control CompletedThis study tested whether giving the immunotherapy drug pembrolizumab (MK-3475) before standard surgery could help prevent head and neck cancer from coming back. It included 67 adults with advanced, surgically removable head and neck cancer. The main goal was to see if the drug c…
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Mindfulness boosts hope and quality of life in head and neck cancer patients
Symptom relief CompletedThis study looked at whether a mindfulness program (MBSR) can improve quality of life and positive feelings like hope and growth in people newly diagnosed with head and neck cancer. 110 adults who had finished surgery and were getting other treatments took part. The goal was to s…
Matched conditions: CANCER OF HEAD AND NECK
Phase: NA • Sponsor: Universiti Sains Malaysia • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Sound waves zap cancer pain: new procedure offers hope
Symptom relief CompletedThis small pilot study tested a new way to treat severe, opioid-resistant pain in people with head and neck cancer. Using focused ultrasound, doctors created a small lesion in the brain to block pain signals. The study enrolled 6 participants and measured safety and pain relief o…
Matched conditions: CANCER OF HEAD AND NECK
Phase: NA • Sponsor: Jeff Elias, MD • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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Less radiation, fewer side effects: new approach for head and neck cancer
Symptom relief CompletedThis study tested whether a lower dose of radiation after surgery could reduce long-term side effects like dry mouth and swallowing problems in people with head and neck cancer. About 200 patients with certain tumor stages took part. The goal was to keep cancer control high while…
Matched conditions: CANCER OF HEAD AND NECK
Phase: PHASE2 • Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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New imaging technique could predict head and neck cancer treatment success
Knowledge-focused CompletedThis study tested whether a special PET scan (18F-FMISO) can measure low oxygen levels (hypoxia) in head and neck tumors. Sixteen adults with head and neck cancer received the scan before starting radiation therapy. Researchers then checked if the scan results matched treatment o…
Matched conditions: CANCER OF HEAD AND NECK
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated May 26, 2026 12:12 UTC
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New study reveals how cancer treatment affects swelling in the head and neck
Knowledge-focused CompletedThis study looked at 50 people treated for head and neck cancer to see how often swelling (lymphedema) happens after treatment. Researchers measured fluid levels in the head and neck area and asked about quality of life before and after cancer therapy. The goal was to better unde…
Matched conditions: CANCER OF HEAD AND NECK
Sponsor: Lund University • Aim: Knowledge-focused
Last updated May 26, 2026 12:09 UTC