BURNS

This study tests whether a new cream called MW-III can help partial-thickness burn wounds heal faster than the standard treatment, Silvadene. About 60 adults with thermal burns covering up to 25% of their body will be enrolled. The main goal is to see how long it takes for the bu…

This study tests if a common, low-cost drug called tranexamic acid can prevent blood clots under skin grafts in burn patients as well as the standard, more expensive drug thrombin. About 62 adults with small to moderate burns will receive one of the two drugs during their skin gr…

This study tests a blood-filtering device called Efferon LPS NEO in 30 children with severe thermal burns. The device is designed to remove harmful substances from the blood to help the children recover faster. Researchers will compare how long treated children stay in the ICU ve…

This study tests a device called Efferon LPS that filters the blood of adults with severe thermal burns. The goal is to see if it reduces time in the intensive care unit (ICU). Fifteen participants will receive two filtering sessions and be compared to a similar group from past r…

This study tests whether a telerehabilitation program using technology can help adults recovering from burns improve their joint movement and scar healing. About 30 participants will use a smartphone or computer to do rehab exercises at home. The goal is to see if this approach m…

This study tests a gel called Plurogel against standard burn dressings in people with partial thickness burns on the face or one limb. The goal is to see if the gel helps burns heal faster, reduces pain, and lowers the need for skin grafts. About 25 adults will take part, and the…

This study tests whether training with a wearable robot can improve walking ability in people who still have trouble walking at least 6 months after a severe burn injury. Twenty adults who had skin grafts or burns on more than half of their lower body will do robot-assisted walki…

This study tests a gel called PluroGel on burn wounds to see if it helps them heal better than standard dressings. About 20 adults with similar burns on both arms or legs will have one limb treated with PluroGel and the other with standard care. The goal is to see if PluroGel red…

This study tests whether a handheld canister of nitrous oxide (laughing gas) can help control pain and anxiety during burn dressing changes. Thirty adults with burns covering 5-20% of their body will try both the gas and standard care to see which works better. The goal is to fin…

This study tests whether a cream made from 4-aminopyridine (4-AP) can help second-degree burns heal faster and with less scarring. About 200 adults with fresh burns will receive the cream or a placebo. The goal is to see if the treatment reduces the need for skin grafts and impro…

This study tracks how a small amount of glucose spreads in the body of adults with severe burns (covering at least 30% of skin) during their first four days in intensive care. Researchers measure glucose levels before and after a quick injection to calculate the initial distribut…

This study is a large registry that collects data on how a blood-filtering device called CytoSorb is used in real-world intensive care settings. It will include up to 3,000 critically ill patients with conditions like septic shock, severe lung injury, or liver failure. The goal i…