BRCA2 GENE MUTATION
Clinical trials for BRCA2 GENE MUTATION explained in plain language.
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Promising prostate cancer trial for hispanic and black patients pulled before start
Disease control TerminatedThis was a phase 2 trial testing a combination of niraparib and abiraterone plus prednisone for metastatic hormone-sensitive prostate cancer in Hispanic/Latino and Black patients with specific gene mutations. The study aimed to enroll 64 people but was withdrawn before any partic…
Matched conditions: BRCA2 GENE MUTATION
Phase: PHASE2 • Sponsor: Qian Qin • Aim: Disease control
Last updated Jun 23, 2026 11:58 UTC
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Keytruda takes on genetic weak spots in advanced tumors
Disease control OngoingThis phase 2 trial tests whether pembrolizumab (Keytruda) can shrink or control advanced solid tumors that have certain gene mutations (BRCA1, BRCA2, POLE, POLD1). The study enrolled 21 adults with cancers that have spread or come back. Researchers measure how many patients see t…
Matched conditions: BRCA2 GENE MUTATION
Phase: PHASE2 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Jun 23, 2026 11:58 UTC
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New hope for tough cancers: drug targets BRCA mutations
Disease control OngoingThis study tests a drug called talazoparib in 150 people with advanced cancers that have not responded to standard treatments. The drug works by blocking an enzyme that helps cancer cells survive, specifically targeting tumors with changes in BRCA or related genes. The goal is to…
Matched conditions: BRCA2 GENE MUTATION
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 22, 2026 12:06 UTC
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New drug shows promise in shrinking ovarian tumors before surgery
Disease control OngoingThis early-phase trial tested the drug olaparib in 15 people with newly diagnosed BRCA-mutant ovarian, fallopian tube, or peritoneal cancer before they had surgery. The goal was to see if taking olaparib for two cycles could shrink tumors or stop them from growing. Olaparib works…
Matched conditions: BRCA2 GENE MUTATION
Phase: EARLY_PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 10, 2026 13:25 UTC
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Can diet and exercise programs cut cancer risk? new study tests lifestyle changes
Prevention OngoingThis study tests different programs to help people at high risk for cancer (such as those with BRCA or Lynch syndrome) or cancer survivors increase their physical activity and eat healthier. The goal is to see which programs work best to reduce cancer risk. About 337 participants…
Matched conditions: BRCA2 GENE MUTATION
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Prevention
Last updated Jun 12, 2026 12:10 UTC
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Genetic counseling by phone may ease cancer fears in High-Risk women
Knowledge-focused TerminatedThis study looks at whether watching an online genetics video, with or without phone counseling from a genetic counselor, can reduce the stress women feel about their cancer risk. It involves 5,200 women aged 30 or older who have had triple-negative breast cancer and still have a…
Matched conditions: BRCA2 GENE MUTATION
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:05 UTC