BIPOLAR AFFECTIVE DISORDER

This study tests whether adding melatonin to usual treatment helps people with bipolar disorder have more stable moods. About 200 adults will take either melatonin or a placebo daily for 6 months while tracking their mood on a phone app. The goal is to see if melatonin can reduce…

This study tests a smartphone app that teaches cognitive behavioral therapy (CBT) skills to help people with depression feel better. Over 8 weeks, participants use the app for weekly lessons and homework guided by AI. The goal is to see if the app reduces depression symptoms and …

This study tests whether adding lacosamide to standard treatment can reduce depression in people with bipolar disorder who haven't improved with other medications. Forty adults aged 18-65 with moderate to severe depression will receive either lacosamide or a placebo for 12 weeks.…

This study will closely examine the physical and mental health of 100 adults admitted to NHS psychiatric wards. Researchers want to learn how common physical illnesses are in this group and how severe their mental health symptoms are. The goal is to better understand the overall …

This study looks at how well different fitness tests work for people with severe mental illness, like schizophrenia or bipolar disorder. Researchers will compare three methods of measuring fitness in 75 participants (50 with mental illness and 25 healthy controls). The goal is to…