BACTEREMIA

This study tests whether checking vancomycin levels after the first dose and adjusting quickly helps infants with sepsis reach the right drug concentration sooner. About 40 infants under 90 days old will receive model-based dosing and early monitoring. The goal is to improve infe…

This study looks at whether a new, simpler guideline can safely reduce the number of tests, hospital stays, and antibiotics given to infants under 2 months old with fever. Researchers will compare hospitals using the new guideline to those using standard care. The goal is to see …

This study looks at whether people with a staph bloodstream infection and a low VIRSTA score (under 3) can safely avoid routine heart ultrasound (echocardiography). The VIRSTA score helps predict the risk of a serious heart infection called infective endocarditis. 700 adults will…

This study looks at the sticky layer (biofilm) that can form on arterial catheters in intensive care patients. About 60 adults in the ICU will have their catheters examined after removal to see what types of bacteria or fungi are present and how the biofilm is structured. The goa…

This study looks at whether emergency medicine pharmacists can help speed up the review of positive blood culture results for patients who have already left the emergency department. Delays in notifying patients about serious infections can lead to sepsis or death. The study will…