B cell malignancies
Clinical trials for B cell malignancies explained in plain language.
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New combo CAR-T therapy targets multiple cancer proteins
Disease control Stopped earlyThis trial tests a combination of genetically modified immune cells (CAR-T cells) that target CD19 plus another protein on B-cell cancers. The goal is to improve treatment for patients whose cancer has returned or not responded to standard therapy. The study enrolls 100 participa…
Matched conditions: B CELL MALIGNANCIES
Phase 1/2 • Sponsor: Shenzhen Geno-Immune Medical Institute • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Engineered immune cells take on tough blood cancers
Disease control Stopped earlyThis study tests a new treatment called 4SCAR19 cells for people with B-cell cancers that have come back or not responded to standard therapy. The treatment uses a patient's own immune cells, modified in a lab to better find and attack cancer cells. The trial aims to check safety…
Matched conditions: B CELL MALIGNANCIES
Sponsor: Shenzhen Geno-Immune Medical Institute • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Double-Pronged CAR-T cells take aim at Hard-to-Treat blood cancers
Disease control Stopped earlyThis study tests a new type of immunotherapy called bi-specific CAR-T cells that target two proteins, CD19 and CD79b, found on B cell cancers. The therapy involves collecting a patient's own immune cells, modifying them to recognize and attack cancer cells, and infusing them back…
Matched conditions: B CELL MALIGNANCIES
Phase 1/2 • Sponsor: Shenzhen Geno-Immune Medical Institute • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC