B CELL MALIGNANCIES
Clinical trials for B CELL MALIGNANCIES explained in plain language.
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MRNA therapy takes on blood cancer in early human trial
Disease control Not yet recruitingThis early-phase study tests a new mRNA drug (WGb-0301) for people with B-cell blood cancers that have come back or not responded to standard treatments. The drug uses lipid nanoparticles to deliver mRNA that targets CD19 on cancer cells. The main goals are to find a safe dose an…
Matched conditions: B CELL MALIGNANCIES
Phase: EARLY_PHASE1 • Sponsor: Sichuan University • Aim: Disease control
Last updated May 26, 2026 12:02 UTC
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New CAR T-Cell therapy targets Hard-to-Treat blood cancers
Disease control Not yet recruitingThis study tests a new treatment called SHB-02-CD19 for people with certain blood cancers (B-cell malignancies) that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to recognize and attack cancer cells. The goal is …
Matched conditions: B CELL MALIGNANCIES
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Double-Pronged CAR t cells take on tough blood cancers
Disease control Not yet recruitingThis early-phase trial tests a new type of CAR T cell therapy that targets two proteins (CD19 and CD20) on cancer cells. It is for adults with B-cell leukemia or lymphoma who have run out of standard treatments, including commercial CAR T cells. The main goal is to check safety a…
Matched conditions: B CELL MALIGNANCIES
Phase: PHASE1 • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Immune protein study could unlock new cancer clues
Knowledge-focused Not yet recruitingThis study looks at two proteins, CD85d and CD305, that help some B-cell cancers hide from the immune system. Researchers will measure these proteins in 180 newly diagnosed patients to see if they can predict how fast the cancer grows or how well treatments might work. The goal i…
Matched conditions: B CELL MALIGNANCIES
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC
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New study aims to unlock immune secrets of b-cell cancers
Knowledge-focused Not yet recruitingThis study will measure two immune system markers, CD274 and CD276, in blood and bone marrow samples from 159 people newly diagnosed with B-cell cancers like leukemia and lymphoma. The goal is to see if these markers can help doctors better diagnose these cancers and understand w…
Matched conditions: B CELL MALIGNANCIES
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated May 18, 2026 12:02 UTC