B-cell acute lymphoblastic leukemia
Clinical trials for B-cell acute lymphoblastic leukemia explained in plain language.
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Experimental therapy SNC116 put to the test against Hard-to-Treat leukemia
Cure Not yet recruitingResearchers are testing an experimental therapy called SNC116 in adults with B-cell acute lymphoblastic leukemia that has returned or stopped responding to treatment. The early-stage study enrolls about 28 people and focuses on safety, side effects, and how the body processes the…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Early phase 1 • Sponsor: Shanghai Simnova Biotechnology Co.,Ltd. • Aim: Cure
Last updated Sep 21, 2026 20:00 UTC
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Dual-Pronged CAR T-Cell therapy takes aim at Hard-to-Treat leukemia
Disease control Not yet recruitingThis phase 1 trial tests a new cell therapy called KITE-753 for adults with B-cell acute lymphoblastic leukemia (B-ALL) that has come back or not responded to standard treatments. KITE-753 is made from a patient's own immune cells, which are modified to recognize and attack leuke…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Can a new combo drug tame childhood leukemia that Won't quit?
Disease control Not yet recruitingThis trial is investigating whether a new drug called sonrotoclax, when combined with other anti-cancer medicines, is safe and effective for children and adolescents with acute myeloid leukemia (AML) or B-cell acute lymphoblastic leukemia (ALL) that has returned or not responded …
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase 1/2 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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New shot aims to stop hidden leukemia in its tracks
Disease control Not yet recruitingThis study tests whether a drug called blinatumomab, given as a simple injection under the skin, can control small amounts of leftover leukemia cells (called measurable residual disease, or MRD) in adults with B-cell acute lymphoblastic leukemia. The goal is to prevent the cancer…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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New combo therapy aims to treat leukemia without harsh chemo
Disease control Not yet recruitingThis study tests whether combining two drugs, inotuzumab and blinatumomab, is safe and effective for adults newly diagnosed with B-cell acute lymphoblastic leukemia (B-ALL). The trial includes 26 people aged 18 and older who are either 55+ or cannot tolerate standard chemotherapy…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase 1/2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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Double-Pronged immune cells take aim at stubborn blood cancers
Disease control Not yet recruitingThis phase 1 trial tests an experimental therapy called 20-19 Tan BB06z CAR-T for people with certain blood cancers (like lymphoma or leukemia) that have come back or not responded to treatment. The therapy involves taking a patient's own immune T cells, genetically modifying the…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Phase 1 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Colombia launches first CAR-T trial for Hard-to-Treat blood cancers
Disease control Not yet recruitingThis study aims to bring CAR-T cell therapy to Colombia for people with certain blood cancers that have come back or not responded to treatment. It has two parts: first, setting up the necessary partnerships and facilities to produce the therapy locally, and second, testing the s…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Sponsor: GUSTAVO SALGUERO • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New bedside CAR-T treatment aims to tackle blood cancer in adults
Disease control Not yet recruitingThis early-phase study tests a personalized CAR-T cell therapy made at the bedside for adults with B-cell acute lymphoblastic leukemia. The treatment uses the patient's own immune cells to target and kill cancer cells. The main goals are to check safety, find the best dose, and s…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Early phase 1 • Sponsor: The General Hospital of Western Theater Command • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Cord blood CAR-T: a new hope for adults with B-Cell leukemia?
Disease control Not yet recruitingThis early-stage trial is testing a new treatment for adults with B-cell acute lymphoblastic leukemia (B-ALL) using immune cells from donated umbilical cord blood that are engineered to attack cancer cells (UCAR-T). The study will enroll 50 participants to check safety, find the …
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Early phase 1 • Sponsor: The General Hospital of Western Theater Command • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Italian study to track CAR-T success in leukemia patients
Knowledge-focused Not yet recruitingThis observational study will follow 107 children and adults with B-cell acute lymphoblastic leukemia who are treated with approved CAR-T cell therapies in Italy. Researchers will collect data from medical records to see how many patients achieve a response. The goal is to unders…
Matched conditions: B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC