AXIAL SPONDYLOARTHRITIS

This study is testing a live attenuated dengue vaccine (Butantan-DV) in people aged 12–59 with autoimmune rheumatic diseases like rheumatoid arthritis or lupus, who are stable and on low or no immune-suppressing drugs. Researchers want to see if the vaccine is safe and triggers a…

This study tests an experimental drug called SPY002-072 in 285 adults with moderately to severely active rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis. Participants receive either the drug or a placebo to see if it reduces joint pain, swelling, and inflamm…

This study compares two ways of giving bimekizumab—an IV infusion versus a standard shot—to see if the IV works just as well. About 392 adults with active psoriatic arthritis or axial spondyloarthritis will take part. The main goal is to check drug levels in the blood and watch f…

This study follows 2,250 adults in China with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine and joints) to understand how the disease progresses over time. Researchers will measure changes in physical function, spinal damage on X-rays, and episodes…

This study looks at how much of the drug bimekizumab passes into the breast milk of mothers who are already taking it for conditions like psoriasis or arthritis. About 20 breastfeeding women will provide milk samples over several weeks. The goal is to understand possible exposure…