Autoimmune hepatitis

This study tested a new biologic drug called VAY736 in 68 adults with autoimmune hepatitis who did not get better with or could not tolerate standard treatments. The goal was to see if VAY736 could safely help normalize liver enzyme levels. Participants received either VAY736 or …

This study tested a new drug called zetomipzomib in 24 adults with autoimmune hepatitis, a condition where the immune system attacks the liver. Participants received either the drug or a placebo along with their usual treatment for 24 weeks, with an option to continue the drug fo…

This study tested how well a special MRI scan called LiverMultiScan can measure liver fat, iron, and scarring. 61 adults with various liver diseases had up to 6 scans on different machines. The goal was to see if the results are consistent when repeated on the same scanner or on …

This completed study looked at whether lupus patients already taking hydroxychloroquine long-term had a lower risk of catching COVID-19 or developing severe symptoms. Researchers compared 552 patients who either took the drug or did not, using blood tests and questionnaires. The …

This study is collecting blood, urine, and stool samples from 500 children with autoimmune diseases and healthy controls. Researchers will analyze these samples to find molecular patterns that could help diagnose these conditions and guide treatment decisions. The goal is to crea…

This study aims to identify the unique molecular signature of immune cells called T cells that mistakenly attack the liver in autoimmune liver diseases like autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis. Researchers will analyze blood sampl…

This study tests whether artificial intelligence can help doctors tell the difference between drug-induced liver injury and autoimmune hepatitis, two conditions that look very similar. Researchers are building a machine learning model using data from over 2,500 patients. If it wo…