ANEURYSMAL SUBARACHNOID HEMORRHAGE

This study will test whether a non-invasive device that stimulates the vagus nerve (via the ear) can reduce brain damage and inflammation in people with acute brain injury. Sixty adults with traumatic brain injury or bleeding around the brain will receive either real or sham stim…

This study tests whether a stellate ganglion block (a nerve block injection) can improve neurological outcomes in people who have had a bleeding stroke from a ruptured aneurysm. The procedure is done before surgery to reduce brain artery spasms and improve blood flow. Researchers…

This study tests whether adding the drug cilostazol to standard care helps people recover better after a brain bleed caused by a ruptured aneurysm. About 630 adults will receive either cilostazol or a placebo for 14 days, and their recovery will be checked at 6 months. The goal i…

This study tests a drug called tirofiban, which stops blood clots from forming, in people who have had a bleeding aneurysm in the brain. The goal is to find the safest dose and see if it can prevent delayed brain damage. About 82 adults aged 18-85 will take part, and the study wi…

This study tests whether the drug cilostazol can prevent delayed brain injury (called delayed cerebral ischemia) in people who have had a bleeding aneurysm. About 316 adults aged 18-80 who had surgery to fix the aneurysm will be randomly assigned to receive either cilostazol or a…

This study looks at whether raising blood pressure soon after surgery for a ruptured brain aneurysm can improve recovery in people with subarachnoid hemorrhage. About 750 adults who had aneurysm repair will be randomly assigned to have their blood pressure raised or lowered withi…

This study looks at whether people who have had a ruptured brain aneurysm also have an abdominal aortic aneurysm (a bulge in the main belly artery) that they don't know about. About 233 participants will get a painless belly ultrasound to check. The goal is to see how common this…

This study looks at blood markers related to inflammation and clotting in people who have had a stroke or a brain bleed. Researchers want to see how these markers change over time and differ between patients with complications. About 499 adults will give blood samples at five tim…

This study will track 1000 adults who had a brain bleed from a burst aneurysm. The goal is to learn how often delayed brain injury happens and how doctors currently diagnose and treat it. By comparing different hospital approaches, researchers hope to find better ways to prevent …