Could a gentle zap to the ear help heal brain injuries?
NCT ID NCT07384845
First seen Feb 03, 2026 · Last updated Jun 23, 2026 · Updated 19 times
Summary
This study will test whether a non-invasive device that stimulates the vagus nerve (via the ear) can reduce brain damage and inflammation in people with acute brain injury. Sixty adults with traumatic brain injury or bleeding around the brain will receive either real or sham stimulation. Researchers will measure brain injury markers and inflammation levels in blood and spinal fluid to see if the device helps.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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UHCZagreb
Zagreb, 10000, Croatia
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcutaneous vagus nerve stimulation (tVNS) device
What this could lead to
If it works, this could point toward a non-invasive way to protect the brain and reduce harmful inflammation after a brain injury.
What could go wrong
This is a very early, small trial (60 people) that hasn't started yet. The device may not show a clear benefit, and results may not apply to all types of brain injury.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.