AMYLOIDOSIS

This study tested whether adding daratumumab to standard chemotherapy (CyBorD) helps people newly diagnosed with AL amyloidosis, a rare disease where abnormal proteins build up in organs. About 416 adults took part. The goal was to see if the combination leads to better blood res…

This study tested whether a special PET/MR scan using a radioactive tracer called F-18 florbetapir can detect amyloid protein buildup in the nerves of people with amyloidosis. Eight adults with confirmed nerve amyloidosis or other nerve diseases took part. The goal was to see if …

This phase 2 study tested a radioactive tracer called 124I-AT-01 in 33 people with systemic amyloidosis. The goal was to see how well PET/CT scans could measure amyloid buildup in organs like the heart and kidneys, and whether the results were consistent when repeated. The study …

This study followed 37 people with a genetic risk for hereditary ATTR amyloidosis over five years. Researchers measured levels of misfolded proteins in the blood to see if they could detect the earliest signs of the disease. The goal is to develop a way to catch the condition bef…

This study looked at 721 Russian patients with carpal tunnel syndrome to see how many also had a rare inherited nerve disease called hereditary transthyretin amyloidosis. Researchers reviewed medical records and did genetic testing. The goal was to understand how common this cond…

This study looked at 51 adults with cardiac amyloidosis, a rare heart condition, to find out how many also have problems with smell and taste. Researchers used simple tests to measure these senses. The goal was to see if smell or taste loss could help doctors catch the disease ea…