AMYLOIDOSIS

This study tested whether adding daratumumab to standard chemotherapy (CyBorD) helps people newly diagnosed with AL amyloidosis, a rare disease where abnormal proteins build up in organs. Over 400 adults took part. The goal was to see if the combination leads to better blood resp…

This study tested whether a special PET/MR scan using a tracer called F-18 florbetapir can help doctors see amyloid buildup in the nerves of people with amyloidosis. Eight adults with confirmed nerve amyloidosis or other nerve diseases took part. The goal was to see if the scan c…

This study tested a new radioactive tracer called 124I AT-01 to see how well it can measure amyloid protein buildup in organs like the heart, kidneys, liver, and spleen using PET/CT scans. Thirty-three adults with systemic amyloidosis (AL or ATTR type) were scanned twice, six wee…

This study followed 37 people with a genetic risk for hereditary ATTR amyloidosis over five years. Researchers measured a specific misfolded protein in the blood to see if it could signal when the disease starts or worsens. No treatments were tested; the goal was simply to learn …

This study looked at 51 adults with cardiac amyloidosis, a condition where protein buildup damages the heart. Researchers tested their sense of smell and taste to see how common these problems are. The goal is to find early warning signs that could lead to faster diagnosis and tr…

This study looked at medical records of 721 Russian patients who had surgery for carpal tunnel syndrome to see how many also have a rare inherited nerve disease called hereditary transthyretin amyloidosis. The goal was to measure how common this disease is in that group. No treat…