ALZHEIMERS DISEASE

This study tests an experimental drug called trontinemab in 800 people with early Alzheimer's (mild cognitive impairment to mild dementia). The goal is to see if it can slow down memory and thinking problems over 72 weeks. Participants will receive either the drug or a placebo, a…

This study tests an experimental drug called trontinemab in 800 people with early Alzheimer's (mild memory loss to mild dementia). The goal is to see if it can slow down the disease. Participants will receive either the drug or a placebo, and neither they nor their doctors will k…

This study tests a nasal spray called foralumab in 16 people with early Alzheimer's or mild cognitive impairment. The spray aims to reduce brain inflammation by calming overactive immune cells. Participants will use the spray three times a week for eight weeks and have brain scan…

This study tests whether investigational drugs can prevent or slow the buildup of harmful proteins in the brain that lead to Alzheimer's. It involves 280 adults who carry a genetic mutation that almost guarantees they will develop the disease. The goal is to see if early treatmen…

This study is a pre-screening program to identify people who may be eligible for future Alzheimer's treatment studies. It involves a blood test for a key Alzheimer's protein (pTau217) and a memory test. Up to 13,000 adults with memory concerns will participate, but no treatment i…

This study tests whether music therapy can alter brain-related molecules found in saliva. Researchers will measure chemicals like serotonin and amyloid-beta in 60 older adults, including those with Alzheimer's or mild memory problems. The goal is to provide scientific proof of mu…