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Neck surgery may flush Alzheimer's waste from brain, new trial hopes

NCT ID NCT07073066

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 29 times

Summary

This study tests if a surgery on neck lymph vessels can slow memory decline in people with moderate-to-severe Alzheimer's. 376 participants will either get the surgery plus usual care or just usual care. The goal is to see if the surgery helps clear brain waste and reduces dementia symptoms over 12 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hopital, Capital Medical University

    RECRUITING

    Beijing, 100070, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dongguan Chashan Hospital

    RECRUITING

    Dongguan, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • First Affiliated Hospital of Shandong First Medical University

    ACTIVE_NOT_RECRUITING

    Jinan, Shandong, 250000, China

  • Guangdong Second People's Hospital

    RECRUITING

    Guangdong, Guangzhou, 510000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jining First People's Hospital

    RECRUITING

    Jining, Shandong, 272000, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • Shandong Provincial Public Health Clinical Center

    RECRUITING

    Jinan, Shandong, 250000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Shandong Provincial Third Hospital

    RECRUITING

    Jinan, Shandong, 250000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Affiliated Hospital of Ningbo University

    RECRUITING

    Ningbo, Zhejiang, 315000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Zhengzhou Central Hospital

    RECRUITING

    Zhengzhou, Henan, 450000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.