ALZHEIMERS DISEASE

This Phase 3 trial tests whether trontinemab can slow down Alzheimer's in people with early symptoms like mild memory problems. About 800 volunteers will receive either the drug or a placebo by IV for 72 weeks. The study measures changes in thinking, daily function, and safety.

This Phase 3 trial tests whether the drug trontinemab can slow the progression of early Alzheimer's disease. About 800 people with mild cognitive impairment or mild dementia due to Alzheimer's will receive either the drug or a placebo intravenously. The study will measure changes…

This study tests a nasal spray called foralumab in 16 people with early Alzheimer's or mild cognitive impairment. The spray aims to reduce brain inflammation by calming overactive immune cells. Participants will use the spray three times a week for eight weeks and have brain scan…

This study tests if a surgery on neck lymph vessels can slow memory decline in people with moderate-to-severe Alzheimer's. 376 participants will either get the surgery plus usual care or just usual care. The goal is to see if the surgery helps clear brain waste and reduces dement…

This study tests a drug called remternetug in people who have a strong genetic risk for Alzheimer's but do not yet have symptoms. The goal is to see if the drug can prevent or slow the buildup of harmful proteins in the brain. About 280 participants will receive either the drug o…

This study tests whether experimental drugs can prevent or slow the buildup of harmful proteins in the brain that lead to Alzheimer's disease. It involves 280 adults who carry a genetic mutation that almost guarantees they will develop Alzheimer's. The goal is to see if early tre…

This study is a large-scale screening program to find people who may be eligible for Roche's Alzheimer's drug trials. It involves a simple blood test and a memory assessment. Up to 13,000 participants with memory concerns will be evaluated. No experimental treatment is given in t…

This study aims to scientifically prove that music therapy affects the brain in people with Alzheimer's disease. Researchers will measure brain-related molecules (like serotonin and dopamine) in saliva before and after music sessions. The study includes 60 adults: 20 with Alzheim…

This study looks at how people with mild cognitive impairment (MCI) and Alzheimer's disease adjust their walking when conditions change, like walking on different surfaces. Researchers will measure walking patterns, memory, and thinking skills in 10 older adults. The goal is to b…