Alzheimer disease, early onset
Clinical trials for Alzheimer disease, early onset explained in plain language.
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Could brain pacemakers slow Alzheimer's? new trial tests DBS
Disease control By invitation onlyThis study tests whether deep brain stimulation (DBS) can improve thinking and memory in people with early Alzheimer's disease. Two participants will have electrodes implanted in a brain area that produces a key chemical for memory. The goal is to see if daily, one-hour stimulati…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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New Alzheimer's drug shows promise in Early-Stage trial
Disease control OngoingThis study tests a new drug called PMN310 in people with early Alzheimer's disease. The goal is to see if it is safe and if it can reduce signs of the disease in the brain. About 144 participants will receive multiple doses of the drug or a placebo. This is an early-phase trial, …
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase 1 • Sponsor: ProMis Neurosciences, Inc • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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New Alzheimer's drug THN391 enters first patient trial
Disease control OngoingThis study tests an experimental drug called THN391 in 15 people with early Alzheimer's disease who also have small vessel disease in the brain. Participants receive three monthly IV infusions of either THN391 or a placebo. The main goal is to check safety and how the drug behave…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase 1 • Sponsor: Therini Bio, Inc. • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Can 'Zombie Cell' cleaners fight Alzheimer's? new trial tests idea
Disease control OngoingThis phase 2 trial is testing whether a combination of two drugs, dasatinib and quercetin, is safe and feasible for people with early-stage Alzheimer's or mild cognitive impairment. The drugs aim to clear aging 'senescent' cells that may contribute to brain damage. 48 participant…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Phase 2 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Could a zapping cap help Alzheimer's patients remember?
Symptom relief OngoingThis study tests whether a safe, painless brain stimulation technique called tDCS can improve verbal learning in people with Alzheimer's disease. Researchers will compare active stimulation to a sham (fake) version in 90 participants with typical or language-based Alzheimer's. Th…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jul 17, 2026 00:00 UTC
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Could magnetic pulses sharpen memory in early Alzheimer's?
Symptom relief By invitation onlyThis study tests whether a non-invasive brain stimulation technique called theta-burst stimulation (TBS) can improve cognitive function in people diagnosed with young-onset Alzheimer's disease (before age 65). Seventy participants will receive TBS to a specific brain area, and re…
Matched conditions: ALZHEIMER DISEASE, EARLY ONSET
Sponsor: Chang Gung Memorial Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC