ALCOHOLISM

This study tested whether giving people with alcohol dependence a one-month course of diazepam (40 mg per day) after detoxification could reduce the chance of relapsing into drinking within the next three months. The standard detoxification treatment is usually about one week. Th…

This early-phase pilot study tested whether combining topiramate (a seizure medication) with N-acetyl cysteine (a supplement) is safe and tolerable for people with alcohol use disorder. Seventeen adults who were heavy drinkers and seeking treatment took either the combination or …

This study tested whether the drug baclofen helps people with alcoholism reduce their drinking to safe levels or stop completely over one year. 323 adults who wanted to cut back or quit alcohol took either baclofen or a placebo pill. The goal was to see if more people on baclofen…

This small pilot study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) could improve cognitive flexibility in people recently detoxified from alcohol. Fourteen adults with alcohol use disorder received either re…

This study looked at whether adults with ADHD are more likely to relapse into drinking after completing a detox program. Researchers followed 113 people for 12 weeks, using interviews and questionnaires to assess ADHD and other mental health conditions. The goal was to see if ADH…

This study explored whether gut bacteria differ between people with alcohol use disorder who are currently drinking, those who are abstinent, and healthy moderate drinkers. Researchers collected stool samples, measured cravings in a bar-like setting, and tracked diet and activity…

This study looked at how sleep problems might lead to relapse in people recovering from alcohol dependence. Researchers followed 198 adults leaving inpatient treatment, using sleep questionnaires and activity monitors to track sleep quality. The goal was to understand if poor sle…

This study tested a mobile app called WisePath designed to help adults who are thinking about suicide and may also misuse alcohol. Over 12 weeks, 127 participants either used the WisePath app or received standard self-help resources. Researchers measured changes in suicidal thoug…