Zapping the brain to beat alcohol cravings?
NCT ID NCT03969251
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small pilot study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) could improve cognitive flexibility in people recently detoxified from alcohol. Fourteen adults with alcohol use disorder received either real or sham stimulation to the left prefrontal cortex. The main goal was to see if the treatment helped with tasks measuring thinking flexibility, attention, and memory, not to directly reduce drinking.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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14 people
The number who actually took part.
- Started
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Jul 2019
- Finished
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Feb 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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22 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Right handed males and females who have given written informed consent. * Age 22 years and above with a history of alcohol use disorder * Good physical health * Have a current diagnosis of alcohol use disorder * Reports at least 4 "heavy drinking days" on average in the past 30 days. * Have a BAC by breathalyzer equal to 0.000 when the participants signed the informed consent document * Six months stability on any psychotropic medications * Not have any unresolved legal problems that could jeopardize continuation or completion of the study. * Be able to provide written informed consent, able to understand written and oral instructions in English and be able to complete the questionnaires required by the protocol. Exclusion Criteria: Please contact site for additional information.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UVA Center for Leading Edge Addiction Research
Charlottesville, Virginia, 22903, United States
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