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Zapping the brain to beat alcohol cravings?

NCT ID NCT03969251

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) could improve cognitive flexibility in people recently detoxified from alcohol. Fourteen adults with alcohol use disorder received either real or sham stimulation to the left prefrontal cortex. The main goal was to see if the treatment helped with tasks measuring thinking flexibility, attention, and memory, not to directly reduce drinking.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

14 people

The number who actually took part.

Started

Jul 2019

Finished

Feb 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

22 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Right handed males and females who have given written informed consent. * Age 22 years and above with a history of alcohol use disorder * Good physical health * Have a current diagnosis of alcohol use disorder * Reports at least 4 "heavy drinking days" on average in the past 30 days. * Have a BAC by breathalyzer equal to 0.000 when the participants signed the informed consent document * Six months stability on any psychotropic medications * Not have any unresolved legal problems that could jeopardize continuation or completion of the study. * Be able to provide written informed consent, able to understand written and oral instructions in English and be able to complete the questionnaires required by the protocol. Exclusion Criteria: Please contact site for additional information.

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Conditions

The condition(s) this trial relates to.

alcohol abuse Behavior, Addictive

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UVA Center for Leading Edge Addiction Research

    Charlottesville, Virginia, 22903, United States

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Other studies related to the condition(s) this trial covers.