ADVERSE CHILDHOOD EXPERIENCES

This study tests a program called GRIT, where community health workers coach teens (ages 11-14) and their families on self-regulation skills over six video sessions. The goal is to prevent early, regular use of alcohol and cannabis in youth who have experienced four or more adver…

This study is testing whether adding a family advocate to a proven parenting program can help prevent substance use and reduce childhood trauma in 36 communities. About 360 families with at least one adult caregiver and one adolescent will take part. The goal is to see if the ext…

This study looks at how tough childhood experiences change brain function and reactions to nicotine in 150 non-smoking young adults aged 18-21. Participants receive a tiny dose of nicotine or a placebo nasal spray, then answer questions and have brain scans. The goal is to unders…

This study looks at how violence in schools and the safety steps schools take afterward impact the mental health and learning of students and staff. About 2,500 people from middle and high schools across the U.S. will fill out surveys. The goal is to find out if certain safety st…

This study looks at how difficult childhood experiences and sleep problems might damage blood vessels in young adults aged 18-29. Researchers will track sleep at home and test blood vessel function. Some participants will get a sleep improvement program to see if better sleep hel…

This study looks at how early childhood experiences—like stress, social factors, and breastfeeding—affect the health of children with sickle cell disease. Researchers will enroll 20 mothers and their infants in Birmingham, Alabama. The goal is to learn whether a community-based b…

This study tests a program that brings together pediatricians, community health workers, and parenting educators to support families with adverse childhood experiences (ACEs). The goal is to lower stress and improve health in children ages 3 to 11. Researchers will compare famili…