Advanced melanoma
Clinical trials for Advanced melanoma explained in plain language.
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Can a DNA vaccine teach the immune system to hunt melanoma?
Disease control Not yet recruitingResearchers are testing whether adding an experimental DNA vaccine called iSCIB1+ to standard immunotherapy drugs nivolumab and ipilimumab helps people with advanced melanoma that cannot be removed by surgery. About 550 participants will be randomly assigned to receive either the…
Matched conditions: ADVANCED MELANOMA
Phase 3 • Sponsor: Scancell Ltd • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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Could the time of day you get immunotherapy boost its power against melanoma?
Disease control Not yet recruitingThis study looks at whether giving immunotherapy infusions in the morning improves outcomes for people with advanced melanoma. Researchers will compare morning versus afternoon/evening dosing in 108 participants. The goal is to see if aligning treatment with the body's natural im…
Matched conditions: ADVANCED MELANOMA
Phase 2 • Sponsor: Swiss Cancer Institute • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Personalized cell therapy takes on advanced melanoma in new trial
Disease control Not yet recruitingThis Phase 2 trial tests whether a personalized cell therapy called HS-IT101 works better than chemotherapy for people with advanced melanoma that has stopped responding to standard treatments. HS-IT101 uses a patient's own immune cells, grown in large numbers in a lab, to fight …
Matched conditions: ADVANCED MELANOMA
Phase 2 • Sponsor: Qingdao Sino-Cell Biomedicine Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Fasting during immunotherapy: a new way to boost treatment?
Symptom relief Not yet recruitingThis study looks at whether intermittent fasting is safe and doable for people with advanced solid tumors who are starting immunotherapy. About 90 participants will be split into three groups: no fasting, eating only during an 8-hour window each day, or fasting every other day. R…
Matched conditions: ADVANCED MELANOMA
Sponsor: West Virginia University • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Can a PET scan find the best tumor site for harvesting Cancer-Fighting cells?
Knowledge-focused Not yet recruitingResearchers are testing whether a PET scan that highlights CD8 immune cells can show the best place to collect tumor-infiltrating lymphocytes (TILs) from patients with advanced melanoma. Participants receive standard TIL therapy and also undergo an extra tumor sample from the sit…
Matched conditions: ADVANCED MELANOMA
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Sep 17, 2026 00:00 UTC