Acute on chronic liver failure (ACLF)
Clinical trials for Acute on chronic liver failure (ACLF) explained in plain language.
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Artificial liver device tested in humans for first time
Disease control CompletedThis early-stage trial tested a device called miroliverELAP, which uses a bioengineered liver graft to filter blood outside the body, in 10 adults with acute liver failure. The goal was to check safety and see if it can support the liver for up to 48 hours, giving time for recove…
Matched conditions: ACUTE ON CHRONIC LIVER FAILURE (ACLF)
Phase 1 • Sponsor: Miromatrix Medical Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Can viral markers predict who survives hepatitis b liver failure?
Knowledge-focused CompletedThis observational study follows people with hepatitis B-related acute-on-chronic liver failure who receive one of three antiviral drugs: entecavir, tenofovir alafenamide, or tenofovir amibufenamide. Researchers measure two newer virological markers, HBV RNA and HBcrAg, over time…
Matched conditions: ACUTE ON CHRONIC LIVER FAILURE (ACLF)
Sponsor: Tongji Hospital • Aim: Knowledge-focused
Last updated Sep 13, 2026 00:00 UTC