ACUTE MYELOID LEUKEMIA WITH NPM1 MUTATION
Clinical trials for ACUTE MYELOID LEUKEMIA WITH NPM1 MUTATION explained in plain language.
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New drug combo targets Hard-to-Cure leukemia in early trial
Disease control Recruiting nowThis early-phase study tests whether combining two targeted drugs, SNDX-5613 and gilteritinib, is safe and effective for adults with a specific type of acute myeloid leukemia (AML) that has returned or not responded to treatment. The leukemia must have a FLT3 gene mutation plus e…
Matched conditions: ACUTE MYELOID LEUKEMIA WITH NPM1 MUTATION
Phase: PHASE1 • Sponsor: Uma Borate • Aim: Disease control
Last updated May 26, 2026 12:06 UTC
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New combo therapy aims to improve leukemia treatment
Disease control Recruiting nowThis early-phase trial tests the safety and best dose of a new targeted drug (SNDX-5613) when added to standard chemotherapy for adults with a specific type of acute myeloid leukemia (AML) that has changes in the NPM1 or MLL genes. The study enrolls 28 newly diagnosed patients ag…
Matched conditions: ACUTE MYELOID LEUKEMIA WITH NPM1 MUTATION
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 14, 2026 12:04 UTC