ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Clinical trials for ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE explained in plain language.
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Promising new combo therapy for infant leukemia enters phase 2 trial
Disease control Recruiting nowThis study tests whether adding two targeted drugs, blinatumomab and venetoclax, to standard chemotherapy can better treat infants with a type of leukemia called acute lymphoblastic leukemia (ALL). About 153 infants up to 1 year old will take part. The goal is to see if these com…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 26, 2026 07:03 UTC
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New hope for tough leukemias: targeted drug revumenib enters key trials
Disease control Recruiting nowThis study tests a new drug called revumenib in people with certain types of leukemia that have returned or not improved with standard treatments. The trial has two parts: first, finding the safest dose, then testing how well it works in four specific groups of patients. About 44…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE1, PHASE2 • Sponsor: Syndax Pharmaceuticals • Aim: Disease control
Last updated May 26, 2026 06:51 UTC
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New cord blood transplant trial offers hope for tough blood cancers
Disease control Recruiting nowThis study tests a refined cord blood transplant method for people with hard-to-treat blood cancers like leukemia and lymphoma. Participants receive chemotherapy and radiation before the transplant to kill cancer cells and prepare the body, then donor stem cells are infused to re…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 26, 2026 06:50 UTC
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New approach aims to stop Graft-Versus-Host disease in young cancer patients
Disease control Recruiting nowThis study tests whether removing a specific type of immune cell (naive T cells) from donated stem cells can prevent chronic graft-versus-host disease (GVHD) in children and young adults with blood cancers. GVHD occurs when donor cells attack the patient's body, causing long-term…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 26, 2026 06:50 UTC
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New drug combo offers hope for rare leukemia patients
Disease control Recruiting nowThis study tests a combination of two drugs, venetoclax and azacitidine, in people newly diagnosed with a rare and hard-to-treat leukemia called acute leukemia of ambiguous lineage. The goal is to see if this treatment can help more patients achieve remission. About 23 participan…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: Sheng-Li Xue, MD • Aim: Disease control
Last updated May 26, 2026 06:44 UTC
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New hope for kids with relapsed leukemia: experimental drug combo enters safety trial
Disease control Recruiting nowThis study tests whether adding a new drug called revumenib to two standard chemotherapy drugs (azacitidine and venetoclax) is safe for children and young adults whose acute myeloid leukemia (AML) has not responded to treatment or has returned. About 24 participants will receive …
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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New hope for seniors with aggressive leukemia: chemo plus transplant combo
Disease control Recruiting nowThis study tests a treatment for adults aged 60 and older with newly diagnosed, high-risk acute myeloid leukemia (AML) or similar blood cancers. The approach combines strong chemotherapy (FLAG-Ida) with a donor stem cell transplant shortly after, aiming to shorten the dangerous p…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 18, 2026 12:04 UTC
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New combo therapy aims to tackle tough blood cancers in kids
Disease control Recruiting nowThis early-phase study tests a drug called venetoclax combined with standard chemotherapy for children, teens, and young adults with aggressive blood cancers like leukemia and myelodysplastic syndrome. The goal is to find the safest dose and understand side effects. About 30 part…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE1 • Sponsor: Andrew E. Place, MD • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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New drug shows promise in preventing leukemia return after transplant
Disease control Recruiting nowThis early-phase study tests the safety and best dose of revumenib, a drug that blocks a protein fueling leukemia growth, in 27 adults and children with specific genetic types of acute leukemia. Participants take revumenib after a stem cell transplant to help keep the cancer from…
Matched conditions: ACUTE LEUKEMIA OF AMBIGUOUS LINEAGE
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 12, 2026 13:42 UTC