ACUTE HEART FAILURE

This study tests whether starting the drug finerenone early in the hospital helps people with acute heart failure. About 550 adults with a certain type of heart failure will receive either finerenone or a placebo. The goal is to see if the drug reduces deaths, prevents worsening …

This study tests whether the drug finerenone can reduce heart failure events and deaths in people hospitalized with acute heart failure who have a mildly reduced or preserved pumping ability. About 5,200 participants will receive either finerenone or a placebo. The goal is to see…

This study tests whether using lung ultrasound to guide fluid removal in adults hospitalized for acute heart failure leads to better outcomes than standard physical exams. Researchers will compare hospital stay length, readmission rates, and symptom improvement in 222 participant…

This study tests whether empagliflozin, a drug already used for diabetes, can help people hospitalized with acute heart failure. About 444 adults will receive either the drug or a placebo to see if it reduces the risk of death, rehospitalization, or worsening symptoms within 90 d…

This study tests whether a drug that widens blood vessels (nitrates) works better than a standard water pill (furosemide), or if using both together is best, for people with sudden fluid buildup in the lungs from heart failure. About 1,100 adults with severe shortness of breath a…

This study observes 270 adults hospitalized with acute heart failure to identify different patterns of fluid buildup (congestion). Researchers will use ultrasound and other imaging to measure how the body responds to treatment and track outcomes like hospital stay length and reho…

This study is observing 1,000 people hospitalized with acute heart failure to learn how to better predict their outcomes. Researchers will use blood tests, imaging, and other measurements to identify patterns. The goal is to improve care for future patients, not to test a new tre…

This study tests whether MRI can accurately measure fluid buildup in the lungs of people hospitalized for acute heart failure. Researchers will track how lung water changes during treatment and see if these measurements can predict who is at higher risk of returning to the hospit…