ACUTE HEART FAILURE

This study tested two different oxygen goals in 122 people hospitalized with acute heart failure and fluid in their lungs. One group aimed for 96% oxygen in the blood, the other for 90%. The goal was to see which oxygen level better reduces lung fluid and helps recovery. The stud…

This study tested a device called preCARDIA in 60 people with severe, worsening heart failure. The device temporarily blocks a large vein in the chest to help the heart pump better. The main goal was to see if the device is safe and works as intended.

This study tested whether a structured plan for giving diuretics (water pills) to patients hospitalized with worsening chronic heart failure is safer and more effective than usual care. About 299 adults took part. The goal was to see if the protocol could better manage fluid buil…

This study looked at whether a 7-day course of the steroid prednisone, started in the emergency department, could lower inflammation in people with acute heart failure. Only 3 patients were enrolled, and the main goal was to measure changes in a blood marker called C-reactive pro…

This study looked at whether adding empagliflozin (a diabetes drug) to standard water pills helps people with acute heart failure and moderate-to-severe kidney disease urinate out more excess fluid. 25 adults participated, and researchers measured urine output after combining the…

This study looked at whether a 7-day course of prednisone, a steroid, can lower inflammation in people with acute heart failure. 101 adults from the emergency department took part. The main goal was to see if prednisone plus usual care reduced C-reactive protein (a marker of infl…

This study looked at whether measuring a substance called cystatin C in the blood can help doctors spot kidney problems early in people being treated for acute heart failure. Researchers tracked 64 patients during their hospital stay. The goal was to understand how cystatin C lev…