ACUTE CORONARY SYNDROMES

This study tests whether orticumab can reduce inflammation in the coronary arteries of people who have had a heart attack. About 240 participants will receive either orticumab or a placebo for 24 weeks. The main goal is to see if the drug lowers a specific inflammation measure (F…

This study looks for the best type and dose of blood thinner (P2Y12 inhibitor) for people who have had a heart stent placed. After an initial period on two blood thinners, patients switch to one. The goal is to find a dose that keeps blood clotting at a safe level—not too high (w…

This early-stage trial tests whether an experimental drug called UDP-003 is safe in healthy volunteers and people with heart disease. Researchers will give single or multiple doses of the drug or a placebo and monitor for side effects. The study includes 84 participants and is th…

This study tests a new type of heart stent made from magnesium that slowly dissolves over time. It is designed for people with long blockages in their heart arteries. The goal is to see if the stent is safe and works well at keeping arteries open for up to 12 months. About 100 pa…

This study looks at whether adding oregano and basil leaves to the diet can lower inflammation and improve cholesterol in people who have recently had unstable angina. About 70 participants will eat these herbs and have their blood and urine tested. The goal is to see if these co…

This study looks at a new technology called Cor-IS that measures how well blood vessels widen (flow-mediated dilation) in people who have had a heart attack. Researchers will compare this new method with standard ultrasound in 100 patients. The goal is to see if Cor-IS can better…

This study tests a new, quick blood test done right in the emergency room to rule out heart attacks in people with chest pain. The goal is to see if this faster test can get patients discharged sooner compared to the usual lab test, which can take an hour or more. About 1,500 adu…

This study tests whether using a hand fan can prevent or reduce shortness of breath caused by the heart drug ticagrelor. About 110 adults with acute coronary syndrome who are starting ticagrelor will be enrolled. Researchers will track how many people have breathing trouble withi…

This study looks at immune cells called macrophages in the arteries of people with heart disease or poor leg circulation. Researchers will use imaging and blood tests to see how these cells are activated. The goal is to better understand the disease, not to test a new treatment. …