ACUTE BRAIN INJURY

This study involves 660 brain-injured patients on ventilators to see if a simple clinical score helps doctors decide the best time to remove the breathing tube. The goal is to reduce the need to put the tube back in or prevent death within 5 days. Participants are adults aged 18-…

This study tests whether giving a single dose of a common antibiotic soon after a breathing tube is placed can prevent lung infections and improve survival in people with severe brain injuries. About 3,300 adults on ventilators in intensive care will be randomly assigned to recei…

This study tracks how much physical movement (like sitting up or moving limbs) is given to adults with severe brain injury in Scandinavian intensive care units. Researchers will monitor 198 patients to see how the amount and intensity of movement relates to safety and recovery. T…

This study watches 148 adults with acute brain injury who have a drainage tube in their head. Researchers want to see if changes in a natural chemical called lactate in the brain fluid can signal an infection early. The goal is to find better ways to detect and manage these serio…

This study looks at 406 adults with acute brain injury who need a breathing machine. The goal is to find clues that help doctors know when it's safe to remove the breathing tube. By understanding these clues, the study hopes to reduce failed extubations and improve care for these…

This study looks at whether using both lung and brain ultrasound can help doctors choose the best breathing machine pressure for critically ill patients who have both acute respiratory distress syndrome (ARDS) and acute brain injury. The goal is to find a pressure that helps the …