ACUTE BRAIN INJURY

This study is testing a simple 4-point clinical checklist to help doctors decide when it's safe to remove breathing tubes from brain-injured patients who are still unconscious. The goal is to reduce the risk of failed tube removal, which can lead to pneumonia and other complicati…

This large trial is testing if a single dose of a common antibiotic, given soon after a brain-injured patient is put on a breathing machine, can prevent dangerous lung infections (pneumonia). The goal is to see if preventing these infections helps patients survive and recover bet…

This study aims to see if using two types of ultrasound scans—one on the lungs and one on the brain—can help doctors find the best settings for a breathing machine. The goal is to help critically ill patients who have both severe lung injury and a recent brain injury. Researchers…

This study aims to understand and predict when patients with a sudden brain injury can be safely taken off a mechanical ventilator. Researchers will observe 406 adult patients who have been on a ventilator for at least a day. The goal is to gather information to create better gui…

This observational study aims to understand how certain markers in brain fluid can help detect infections in patients with acute brain injuries who have drainage tubes. Researchers will monitor 148 patients in Denmark to see if lactate levels in brain fluid can predict infections…