Xeroderma pigmentosum
MONDO:0019600Xeroderma pigmentosum (XP) is a rare genodermatosis characterized by extreme sensitivity to ultraviolet (UV)-induced changes in the skin and eyes, and multiple skin cancers. It is subdivided into 8 complementation groups, according to the affected gene: classical XP (XPA to XPG) and XP variant (XPV).
Also known as: Kaposi dermatosis, Kaposi disease, XP, angioma pigmentosum atrophicum, atrophoderma pigmentosum, melanosis lenticularis progressiva, pigmented epitheliomatosis, xeroderma of Kaposi
9 clinical trials for this condition and its sub-types, 4 tagged with Xeroderma pigmentosum itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Xeroderma pigmentosum
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Xeroderma pigmentosum group F 1 trial
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Xeroderma pigmentosum group A 0 trials
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Xeroderma pigmentosum group B 0 trials
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Xeroderma pigmentosum group C 0 trials
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Xeroderma pigmentosum group D 0 trials
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Xeroderma pigmentosum group E 0 trials
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Xeroderma pigmentosum group G 0 trials
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New drug combo shows promise for Hard-to-Treat cancers
Disease control CompletedThis early-stage study tested two drugs, cabozantinib and pamiparib, together in 44 people with advanced solid tumors that had stopped responding to standard treatments. The goal was to find the safest dose and understand side effects. The drugs work by blocking certain enzymes t…
Phase 1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Scientists study rare DNA repair diseases to unlock cancer prevention secrets
Knowledge-focused CompletedThis study looked at people with three rare genetic conditions—xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD)—that affect the body's ability to repair DNA. Researchers examined 709 participants to understand how these defects relate to cancer ri…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC