Scientists study rare genetic diseases to unlock secrets of cancer prevention
NCT ID NCT00001813
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 33 times
Summary
This completed study looked at people with three rare genetic diseases that affect the body's ability to repair DNA: xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD). Researchers examined 709 participants, including patients and their family members, to understand how these conditions develop and why only XP increases cancer risk. The goal was to learn more about how DNA repair normally prevents cancer.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for XERODERMA PIGMENTOSUM are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could reveal how DNA repair prevents cancer, potentially guiding future treatments for these rare diseases.
What could go wrong
This is an observational study, not a treatment trial. It aims to understand the diseases, not to test a new therapy, so direct patient benefits are unlikely.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.