Vertebral column disorder
MONDO:0000812A disease involving the vertebral column.
Also known as: disease of spine, disease of vertebral column, disease or disorder of vertebral column, disorder of vertebral column, vertebral column disease, vertebral column disease or disorder, spinal disease
1241 clinical trials for this condition and its sub-types, 82 tagged with Vertebral column disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Vertebral column disorder
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Spinal cord injury 650 trials
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Intervertebral disk degenerative disorder 122 trials · 216 incl. sub-types
3 sub-types
- Lumbar disk degenerative disorder 164 trials
- Cervical disk degenerative disorder 42 trials
- Thoracic disk degenerative disorder 2 trials
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Spinal stenosis 120 trials · 154 incl. sub-types
1 sub-type
- Lumbar spinal stenosis 99 trials
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Vertebral disorder 3 trials · 129 incl. sub-types
3 sub-types
- Spondylitis 8 trials · 119 incl. sub-types Sub-types →
- Spondylolysis 6 trials
- Kummell disease 1 trial
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Vertebral joint disorder 0 trials · 117 incl. sub-types
2 sub-types
- Ankylosing spondylitis 109 trials · 113 incl. sub-types Sub-types →
- Infectious discitis 4 trials Sub-types →
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Lumbar disk disease 82 trials
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Coccygodynia 19 trials
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Spondylocostal dysostosis 5 trials · 8 incl. sub-types
4 sub-types
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Epidural spinal canal neoplasm 3 trials · 5 incl. sub-types
2 sub-types
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Sacrum chordoma 4 trials
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Sacrococcygeal teratoma 2 trials
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Baastrup syndrome 0 trials
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Dropped head syndrome 0 trials
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Lumbosacral lipoma 0 trials
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Tuberculosis, spinal 0 trials
Most studied deeper sub-types
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New putty may help back surgery patients heal faster
Disease control Not yet recruitingThis study looks at a special putty called Fibergraft used in spine surgery to help bones grow together. About 80 adults with back pain or nerve problems from spine issues will get this putty during surgery. Doctors will check how well the bones heal using CT scans and ask patien…
Sponsor: AO Innovation Translation Center • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New study aims to speed up bleeding diagnosis in the operating room
Diagnosis Not yet recruitingThis study compares two ways to diagnose bleeding problems during surgery: a quick bedside test (viscoelastic test) and standard lab tests. The goal is to see which method gives faster results, helping doctors treat bleeding sooner. About 210 adults having high-risk surgeries (li…
Sponsor: Konkuk University Medical Center • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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New study aims to find best pain block for elderly back surgery patients
Symptom relief Not yet recruitingThis study will compare two types of nerve blocks—lumbar paravertebral block and lumbar erector spinae plane block—for pain control after lumbar spine surgery in people aged 65 and older. The goal is to see which block reduces the need for opioid painkillers in the first 48 hours…
Sponsor: Poznan University of Medical Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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AI vs. doctors: who reads brain data better in spine surgery?
Knowledge-focused Not yet recruitingThis study will test whether artificial intelligence programs like ChatGPT can interpret brain monitoring data (BIS) as accurately as experienced clinicians during spine surgery. Researchers will compare AI responses to those of two doctors in 63 patients. The goal is to see if A…
Sponsor: Antalya Health Sciences University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Can your phone measure your spine? new study aims to find out
Knowledge-focused Not yet recruitingThis study will check if two smartphone apps can reliably measure the curve of the spine, compared to a standard tool called a gravity inclinometer. Researchers will take measurements from 60 healthy volunteers aged 18-25, repeating them at different times to see how consistent t…
Sponsor: Ahi Evran University Education and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can simple spine exercises ease office Workers' pain? new study aims to find out
Knowledge-focused Not yet recruitingThis study looks at how common neck and low back pain is among full-time staff at the University of the West Indies, Mona. It also tests whether an eight-week spine-specific exercise program reduces discomfort better than a general exercise program. About 200 staff members will t…
Sponsor: The University of The West Indies • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Massage vs. talk therapy: which changes your brain chemicals more?
Knowledge-focused Not yet recruitingThis study will compare how massage and talk therapy affect stress and bonding hormones (cortisol and oxytocin) in people with chronic neck or back pain. Twenty-five adults with pain lasting at least 3 months will try both treatments in random order. Researchers will measure horm…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Spine study aims to uncover hidden walking clues in older adults
Knowledge-focused Not yet recruitingThis study will observe how different spinal problems—like scoliosis, stenosis, or herniated discs—change the way people walk and use their back muscles. Researchers will compare 120 older adults (age 60+) with these conditions to healthy volunteers using motion cameras and muscl…
Sponsor: Xuanwu Hospital, Beijing • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Could a common painkiller disrupt spine surgery monitoring?
Knowledge-focused Not yet recruitingThis study looks at whether lidocaine, a numbing medicine, changes the signals used to monitor nerves during spine surgery. 44 adults having spine surgery will get either lidocaine or a placebo. The goal is to see if lidocaine affects the nerve monitor readings, which could help …
Phase 4 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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3D goggles may sharpen spine Surgeons' skills
Knowledge-focused Not yet recruitingThis study will test whether 3D endoscopic visualization helps surgeons perform spine surgery tasks faster and with fewer errors compared to standard 2D vision. Six neurosurgery residents will practice on a spine model using both technologies. The goal is to see if 3D can improve…
Sponsor: Felix Corr • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:14 UTC