Vector-borne disease
MONDO:0100120An infectious disease where a pathogen is carried and transmitted by another organism that acts as disease vector.
Also known as: vector-borne infection, vector-borne infectious disease
448 clinical trials for this condition and its sub-types, 9 tagged with Vector-borne disease itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Vector-borne disease
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Malaria 134 trials · 169 incl. sub-types
7 sub-types
- Plasmodium falciparum malaria 78 trials
- Plasmodium vivax malaria 27 trials
- Cerebral malaria 2 trials
- Mixed malaria 1 trial
- Plasmodium malariae malaria 0 trials
- Plasmodium ovale malaria 0 trials
- Blackwater fever 0 trials
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Dengue disease 74 trials
2 sub-types
- Dengue hemorrhagic fever 7 trials Sub-types →
- Asymptomatic dengue 0 trials
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Tick-borne infectious disease 9 trials · 41 incl. sub-types
10 sub-types
- Lyme disease 30 trials
- Tick-borne encephalitis 6 trials
- Ehrlichiosis 1 trial Sub-types →
- Human granulocytic anaplasmosis 1 trial
- Borrelia miyamotoi disease 0 trials
- Omsk hemorrhagic fever 0 trials
- Powassan encephalitis 0 trials
- Queensland tick typhus 0 trials
- Rickettsia helvetica spotted fever 0 trials
- Tick-borne relapsing fever 0 trials
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Chikungunya 31 trials
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Leishmaniasis 8 trials · 27 incl. sub-types
3 sub-types
- Cutaneous leishmaniasis 14 trials Sub-types →
- Visceral leishmaniasis 14 trials
- Mucocutaneous leishmaniasis 3 trials
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Mycobacterium avium complex disease 22 trials
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Schistosomiasis 15 trials · 17 incl. sub-types
7 sub-types
- Schistosoma mansoni infectious disease 4 trials
- Urinary schistosomiasis 3 trials
- Schistosoma japonicum infectious disease 1 trial
- Schistosoma intercalatum infectious disease 0 trials
- Cercarial dermatitis 0 trials
- Intestinal schistosomiasis 0 trials
- Neuroschistosomiasis 0 trials
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Yellow fever 16 trials
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Zika virus infectious disease 15 trials
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Chagas disease 12 trials
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Filarial elephantiasis 9 trials
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Onchocerciasis 9 trials
1 sub-type
- Ocular onchocerciasis 2 trials
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Arbovirus infection 8 trials
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Lassa fever 6 trials
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Crimean-Congo hemorrhagic fever 5 trials
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Mosquito-borne viral encephalitis 0 trials · 5 incl. sub-types
5 sub-types
- Japanese encephalitis 4 trials
- West-Nile encephalitis 1 trial Sub-types →
- La Crosse encephalitis 0 trials
- St. Louis encephalitis 0 trials
- Western equine encephalitis 0 trials
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Listeriosis 4 trials
1 sub-type
- Listeria meningitis 0 trials
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Plague 2 trials · 4 incl. sub-types
3 sub-types
- Pneumonic plague 3 trials
- Bubonic plague 1 trial
- Septicemic plague 0 trials
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Q fever 3 trials
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Rift valley fever 3 trials
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Human African trypanosomiasis 2 trials · 3 incl. sub-types
2 sub-types
- Infection by Trypanosoma gambiense 3 trials
- Infection by Trypanosoma rhodesiense 0 trials
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Typhus 0 trials · 3 incl. sub-types
3 sub-types
- Scrub typhus 3 trials
- Endemic typhus 0 trials
- Epidemic louse-borne typhus 0 trials Sub-types →
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Hantavirus pulmonary syndrome 2 trials
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Relapsing fever 2 trials
2 sub-types
- Louse-borne relapsing fever 0 trials
- Tick-borne relapsing fever 0 trials
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Oropouche fever 1 trial
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Venezuelan equine encephalitis 1 trial
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West Nile fever 1 trial
1 sub-type
- West-Nile encephalitis 1 trial Sub-types →
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Zika virus congenital syndrome 1 trial
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Lymphocytic choriomeningitis 1 trial
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Tungiasis 1 trial
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Spotted fever 0 trials · 1 incl. sub-types
11 sub-types
- Rocky mountain spotted fever 1 trial
- African tick-bite fever 0 trials
- Flinders island spotted fever 0 trials
- Japanese spotted fever 0 trials
- Queensland tick typhus 0 trials
- Rickettsia conorii infectious disease 0 trials Sub-types →
- Rickettsia helvetica spotted fever 0 trials
- Rickettsia parkeri spotted fever 0 trials
- Siberian tick typhus 0 trials
- Pseudotyphus of California 0 trials
- Rickettsialpox 0 trials
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Alkhurma hemorrhagic fever 0 trials
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Argentine hemorrhagic fever 0 trials
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Bolivian hemorrhagic fever 0 trials
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Colorado tick fever 0 trials
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Murray valley encephalitis 0 trials
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O'nyong'nyong fever 0 trials
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Ross river fever 0 trials
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Venezuelan hemorrhagic fever 0 trials
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Whitewater Arroyo hemorrhagic fever 0 trials
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Bacterial esophagitis 0 trials
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Fungal esophagitis 0 trials
1 sub-type
- Esophageal candidiasis 0 trials
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Phlebotomus fever 0 trials
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Rat-bite fever 0 trials
2 sub-types
- Spirillary rat-bite fever 0 trials
- Streptobacillary rat-bite fever 0 trials
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Trench fever 0 trials
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Tularemia 0 trials
6 sub-types
- Gastrointestinal tularemia 0 trials
- Glandular tularemia 0 trials
- Oculoglandular tularemia 0 trials
- Pneumonic tularemia 0 trials
- Typhoidal tularemia 0 trials
- Ulceroglandular tularemia 0 trials
Most studied deeper sub-types
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Can a new vaccine stop malaria in its tracks?
Vaccine Stopped earlyThis early-stage trial is testing a new malaria vaccine candidate, called Pfs48/45, in healthy adults aged 18 to 45 in the UK. The vaccine is designed to block the malaria parasite from spreading, and it's given with an adjuvant called Matrix-M to boost the immune response. The s…
Early phase 1 • Sponsor: University of Oxford • Aim: Vaccine
Last updated Aug 09, 2026 00:00 UTC
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Early malaria vaccine trial halted – what we know
Vaccine Stopped earlyThis early-stage trial tested a new vaccine against Plasmodium vivax malaria, given with an adjuvant to boost immune response. It involved 25 healthy adults in the UK to check safety and immune reactions. The study was terminated early, so full results are not available.
Early phase 1 • Sponsor: University of Oxford • Aim: Vaccine
Last updated Jun 27, 2026 08:12 UTC
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New hope for stubborn lung infection? trial of epetraborole begins, then stops
Disease control Stopped earlyThis study tested an oral drug called epetraborole for people with a tough-to-treat lung infection called MAC lung disease. The trial aimed to see if adding epetraborole to standard treatment could improve symptoms and clear the infection. However, the study was terminated early,…
Phase 2/3 • Sponsor: AN2 Therapeutics, Inc • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New malaria pill for tiny infants studied, but trial stopped early
Disease control Stopped earlyThis study tested a new, easy-to-dissolve malaria tablet in infants and newborns weighing less than 5 kg who had uncomplicated malaria. The goal was to see how the medicine worked in the body, how safe it was, and how well it treated the infection. The trial was stopped early aft…
Phase 2/3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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New inhaled drug aimed at stubborn lung infection shows promise, but trial halted early
Disease control Stopped earlyThis phase 3 study tested an inhaled form of the antibiotic clofazimine added to standard therapy for people with MAC lung disease that did not respond to previous treatment. The goal was to see if the drug could clear the infection from sputum cultures and improve quality of lif…
Phase 3 • Sponsor: Mannkind Corporation • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Wolbachia-Infected mosquitoes released to fight dengue, zika, and chikungunya
Prevention Stopped earlyThis trial tested a method to control mosquito-borne diseases like dengue, Zika, and chikungunya by releasing male Aedes aegypti mosquitoes infected with Wolbachia bacteria. These males mate with wild females, causing their eggs to die, which reduces the mosquito population. The …
Sponsor: Michigan State University • Aim: Prevention
Last updated Jun 27, 2026 11:03 UTC
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Lyme arthritis pain study halted early – what we know
Symptom relief Stopped earlyThis study aimed to see if taking NSAIDs (like naproxen) on a regular schedule could reduce arthritis symptoms and prevent long-term joint problems in people with Lyme disease. Only 3 participants were enrolled before the study was stopped, so no clear conclusions can be drawn. T…
Phase 3 • Sponsor: Desiree Neville, MD • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Leishmaniasis drug candidate tested in humans for first time – study halted early
Knowledge-focused Stopped earlyThis was a first-in-human study to check the safety and how the body processes a single dose of GSK3494245, a potential treatment for leishmaniasis. It involved 59 healthy adults who received up to three increasing doses of the drug or a placebo. The study was terminated early, s…
Phase 1 • Sponsor: GlaxoSmithKline • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC