Vascular occlusion disorder

This study tests a needle-free connector with anti-reflux technology, a special stopper that prevents blood from flowing back into IV catheters. The goal is to see if it reduces complications like blockages, infections, and pain compared to standard connectors. The trial will inv…

Retinal vein occlusion happens when a clot blocks a vein in the eye, leading to vision loss. Current treatments manage the fluid buildup but do not remove the clot. This trial tests whether a robot can safely guide a tiny needle into the blocked vein to inject tPA, a clot-dissolv…

This trial is testing a new stent (a small mesh tube) to treat blockages in the large vein in the abdomen (inferior vena cava) and nearby leg veins. The study involves 136 adults with symptoms like leg ulcers, pain, or swelling. Doctors will place the stent to keep the vein open …

This study tests a new medical device called the GORE VIAFORT stent, which is a small mesh tube placed inside a blocked or narrowed vein in the leg or pelvis to keep it open. The goal is to improve blood flow and reduce symptoms like pain, swelling, and leg ulcers. About 165 adul…

This study looks at whether adding targeted laser treatment to the standard ranibizumab injections can help people with macular edema (swelling) from a central retinal vein occlusion need fewer injections over time. About 88 adults with this condition will receive either injectio…

This study tests whether a pre-filled syringe is as safe as the traditional vial when giving the medicine bevacizumab for certain eye diseases. About 120 people with wet age-related macular degeneration, diabetic macular edema, or branch retinal vein occlusion will receive inject…

This early study tests a new stent, called CGuard Prime, in 15 adults having a stroke from a blocked carotid artery. The goal is to see if placing the stent is safe and helps patients recover better by 90 days. Researchers will also check for complications like bleeding or new st…

This early-stage trial is testing whether it is safe to inject a person's own bone marrow stem cells into their eye to treat vision loss from conditions like macular degeneration and diabetic retinopathy. Fifteen adults with severe vision loss will receive the injection and be mo…

This study looks at a special stent called WRAPSODY used to treat narrowed or blocked veins in people on dialysis. About 500 participants will be followed for up to 24 months to see how well the stent keeps the access site open and safe. The goal is to improve long-term dialysis …

This study tests a new, less invasive drainage procedure for people with advanced neovascular glaucoma whose eye pressure remains high despite treatment. The goal is to safely lower eye pressure and reduce the need for pressure-lowering drugs. The study involves 30 participants a…

This study compares a new numbing gel (chloroprocaine HCl 3%) to standard eye drops plus a shot for pain relief during eye injections. About 236 adults with conditions like diabetic macular edema or age-related macular degeneration will take part. The goal is to see if the gel wo…

This study tests a new medical device that helps close large holes in the main leg artery after certain heart procedures. About 30 adults will be enrolled to see if the device stops bleeding quickly and safely. The goal is to improve recovery and reduce complications.

This study is collecting long-term, real-world data from about 6,000 adults being treated with Roche eye medications (Faricimab or the Port Delivery System with Ranibizumab) for conditions like wet age-related macular degeneration and diabetic macular edema. The goal is to unders…

This study follows 1,000 patients in China who are already receiving faricimab for diabetic macular edema, retinal vein occlusion, or wet age-related macular degeneration. Researchers will collect data from routine clinic visits over one year to see how well the drug works and ho…

This study looks at whether a computer model can predict when stents placed in the leg arteries might break or fail. Researchers will follow 30 adults who receive a stent for blocked leg arteries. The goal is to see if the model can help doctors choose the best treatment and avoi…

This study compares two methods to close the large vein used for implanting a leadless pacemaker: a special closure device versus a figure-of-eight stitch with manual pressure. Researchers will measure how quickly bleeding stops and how soon patients can go home. The goal is to f…

This study aimed to see if using a special pad along with a standard closure device could help patients get out of bed sooner after a heart catheterization. It was planned for adults having the procedure through the groin. However, the study was withdrawn before any participants …