Varicose disease

Researchers are testing a new adhesive system that seals the great saphenous vein in people with varicose veins. The trial compares this adhesive, delivered through a tube, with radiofrequency ablation, a standard treatment that uses heat to close the vein. About 179 adults with …

This trial tests whether adding vacuum compression therapy — a device that applies cycles of pressure and suction to the leg — can improve healing of chronic lower limb ulcers. Adults with ulcers that have not healed despite standard care will receive either standard wound care a…

This study tested a new method called SALFOAM 3% for treating varicose veins in the legs. It involved 35 adults and compared the new method to the standard foam treatment. The goal was to see if the new method closes veins better and causes less skin darkening.

This study tested whether an AI app (IVENUS) could correctly classify the severity of chronic vein disease from leg photos. Over 1,600 patients had their legs photographed, and the app's diagnosis was compared to that of experienced doctors. The goal was to see if the app could r…

This clinical trial investigates whether two existing medications, allopurinol and atorvastatin, can help prevent serious complications in people with stable liver cirrhosis. The study will compare these drugs against a placebo to see if they reduce the number of acute decompensa…

This trial tests whether a short 5-day course of the blood thinners rivaroxaban (Xarelto) or apixaban (Eliquis) can prevent blood clots that sometimes form after laser treatment for varicose veins. Adults with symptomatic vein reflux undergoing laser ablation of the great sapheno…

This study looked at two surgical approaches for varicose veins: removing the main faulty vein and the visible varicose veins all at once, or removing just the main vein first and the varicose veins later. Researchers wanted to see which approach leads to better symptom relief an…

This study compared two ways to numb the leg for outpatient vein ablation surgery: a femoral nerve block (injecting lidocaine near the groin) and low-dose spinal anesthesia (injecting bupivacaine into the spine). Forty adults aged 18-80 with mild to moderate health status took pa…

This study watches and records pain levels at four key moments during radiofrequency ablation for varicose veins—from needle insertion to the end of the procedure. Researchers will look at how factors like age, gender, and body mass index relate to pain. The goal is to find patte…

This study looked at 40 adults undergoing radiofrequency ablation for varicose veins to compare two types of regional anesthesia: spinal anesthesia and a fascia iliaca block. The goal was to see which method leads to better recovery quality, less pain, and faster mobility after t…

This completed study looked at 26,000 patients who had outpatient procedures for blood vessel problems like peripheral artery disease, varicose veins, or dialysis access issues. The goal was to see how safe and effective these procedures are when done in an office-based angiosuit…