Transient myeloproliferative syndrome
MONDO:0008040A myeloid proliferation occurring in newborns with Down syndrome. It is clinically and morphologically indistinguishable from acute myeloid leukemia and is associated with GATA1 mutations. The blasts display morphologic and immunophenotypic features of megakaryocytic lineage. In the majority of patients the myeloid proliferation undergoes spontaneous remission.
Also known as: MST, TAM, TMD, Transient abnormal myelopoiesis associated with Down syndrome, leukemia, transient, of Down syndrome, transient abnormal myelopoiesis, transient leukaemia, transient leurkemia of Down syndrome
3076 clinical trials for this condition and its sub-types, 13 tagged with Transient myeloproliferative syndrome itself.
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Can Blood-Based injections realign the jaw joint?
Disease control OngoingThis trial compares two injection treatments for a common jaw joint problem where the disc slips out of place but returns, causing pain and clicking. One treatment uses a concentrate from the patient's own blood, called platelet-rich fibrin, while the other uses a sugar solution.…
Phase 2 • Sponsor: Cairo University • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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New combo treatment aims to quiet jaw pain for TMD sufferers
Symptom relief OngoingThis study tests whether wearing a custom mouth splint and getting a granisetron injection into the jaw muscle reduces pain from temporomandibular disorders (TMD) better than the splint alone or with lidocaine. About 48 adults with jaw muscle pain will be followed for 6 months. T…
Phase 4 • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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Jaw surgery showdown: which TMJ fix works best?
Symptom relief By invitation onlyThis study looks back at 65 adults who had one of two surgeries for a painful jaw joint condition (TMJ disc displacement). The goal is to see which surgery better improves mouth opening, reduces pain, and helps the jaw work better. Researchers also check recovery speed, side effe…
Sponsor: Karolinska Institutet • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Jaw pain mystery: scientists probe genes and feelings for clues
Knowledge-focused By invitation onlyThis study looks at how chronic jaw muscle pain relates to genetics, blood chemicals, and emotional state. Researchers will compare 102 adults with and without jaw pain to find connections. No treatment is given; the goal is to better understand the condition.
Sponsor: Wroclaw Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC