Jaw pain mystery: scientists probe genes and feelings for clues
NCT ID NCT05676827
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how chronic jaw muscle pain relates to genetics, blood chemicals, and emotional state. Researchers will compare 102 adults with and without jaw pain to find connections. No treatment is given; the goal is to better understand the condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 102 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2023
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Study population will consist of 51 patients with masticatory muscle pain for at least 3 months, diagnosed on basis of DC/TMD protocol
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria for study group: * Masticatory muscle pain for at least 3 months, based on DC/TMD, at least 18 y.o Exclusion Criteria: * severe neurological or psychiatric diseases, use of drugs that may affect the neuromuscular system, alcohol or drug addiction, cancer or pregnancy, previous head surgery Inclusion criteria for control group: * no pain in masticatory muscles, age of at least 18 y.o Exclusion criteria the same as for study group
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Wroclaw Medical University
Wroclaw, Poland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Laser zaps TMJ pain: new study tests quick relief
- New dental MRI could replace x-rays for safer checkups
- New gel could ease jaw pain while you sleep
- Mouthguard study aims to soothe jaw and neck pain
- New combo treatment aims to quiet jaw pain for TMD sufferers