Tongue disorder

This phase 3 trial tested whether adding bevacizumab to standard chemotherapy helps people with head and neck cancer that has returned or spread. About 403 adults took part. The main goal was to see if the combination improved overall survival compared to chemotherapy alone.

This pilot study tests a new surgical technique called the anterolateral thigh myofascial fat composite flap (ALT-MF) for repairing tongue defects after cancer surgery in obese patients (BMI 30 or higher). Traditional flaps can be too bulky in obese patients, leading to problems …

This study tests a new device called SNIP designed to treat tongue-tie in infants. The device is used to perform a frenectomy, a procedure that releases the tight band under the tongue. The study includes 6 infants with anterior tongue-tie and focuses on how easy the device is fo…

This study is testing a device called DaRT that delivers alpha radiation directly into tumors. It is for people with skin cancer, mouth tumors, or superficial soft tissue sarcoma who have not responded to other treatments or cannot have standard therapy. The goal is to see if the…

This phase III trial studies whether adding the drug cetuximab to modern radiation therapy improves survival for people with advanced head and neck cancer that has been surgically removed. About 700 participants received either radiation alone or radiation plus cetuximab. The stu…

This study looks at tongue-tie in newborns and whether treating it helps with breastfeeding. Researchers will follow 300 infants for up to 5 years, comparing different treatments. The goal is to make breastfeeding easier and less painful for mothers.

Researchers at the University of Alberta are following 500 children who had a tongue-tie release as infants to see how often they later develop feeding, speech, dental, or sleep and breathing problems that need further evaluation. Tongue tie is a shortened band under the tongue t…

This study follows 348 infants from birth to age 4 to see how tongue-tie (a tight piece of skin under the tongue) affects breastfeeding, feeding, and speech. Researchers will measure tongue movement and compare different ways to diagnose the condition. The goal is to provide clea…