Tibia fracture

This study tested whether adding tobramycin powder to the standard vancomycin powder in the wound during surgery reduces infections after high-risk leg fracture repair. About 1,550 adults with tibial plateau or pilon fractures at high infection risk took part. The main goal was t…

This trial investigates whether placing vancomycin antibiotic powder directly into the wound during surgery can reduce deep surgical site infections in people with severe tibial plateau fractures. Participants are adults with high-energy fractures requiring plate and screw fixati…

This study looked at whether giving tranexamic acid before surgery can reduce blood loss in people with broken thigh or shin bones. Fifty-four patients received either the drug or a placebo before their operation. Researchers measured blood loss during and after surgery, as well …

This study looked at 442 people with severe open fractures of the shin bone (tibia). It compared two surgical approaches: using a modern ring external fixator (a frame outside the leg) versus internal fixation (a metal rod or plate placed inside the bone). The main goal was to se…

This study looked at whether a one-day course of antibiotics is as good as a three-day course at preventing infections after femur or tibia fracture surgery with a metal rod (intramedullary nailing). Fifty-six adults were randomly assigned to receive either three or nine doses of…

This study tested whether giving patients extra oxygen (80% FiO2) during surgery could reduce surgical site infections after severe tibial plateau or pilon fractures. Over 1,100 patients were randomly assigned to receive either supplemental oxygen or standard care. The main goal …

This study tested a mixture of the patient's own bone, artificial bone substitute, antibiotic, and fresh blood to help heal leg fractures that had not joined properly. Twenty-five adults with broken thigh or shin bones that failed to heal after initial surgery received this compo…

This study tracked 241 adults and teens with broken thigh or shin bones who received either a retrograde femoral nail or a tibial nail. The goal was to see how well the bones healed and if patients had pain. Researchers measured healing time and pain scores to confirm the nails a…

This study tested a new bone graft material (OIF/β-TCP) in 35 people with severe open fractures of the shin bone (tibia). The goal was to see if it helps bones heal when they are slow to mend. Participants were followed for up to 52 weeks after the graft was implanted.

This study tested whether adding photobiomodulation (light therapy) to standard physical therapy helps military trainees with leg stress fractures heal faster. 105 participants received either real or sham light therapy for up to 6 weeks, and researchers tracked how quickly they …

This study tested a high-intensity interval training (HIIT) walking program for people recovering from a broken thigh or shin bone. 66 adults aged 18-50 who had surgery for their fracture took part. The goal was to see if this type of exercise could improve their physical functio…

This study looked at whether starting to put weight on your leg early after ankle fracture surgery helps you recover better than waiting longer. 435 adults who had surgery for certain types of ankle fractures took part. Researchers tracked complications and how quickly people ret…

This study looked back at medical records of 397 patients who had surgery for a broken shinbone (tibia) using either an antibiotic-coated or a standard uncoated titanium nail. The goal was to see if the coated nail reduced infections and improved bone healing. Researchers also ch…

This study examined bacteria in severe leg wounds of 646 adults (ages 18-64) with open tibia fractures or traumatic amputations. Researchers took samples at the time of wound closure to see if certain bacteria led to deep infections within 30 days to one year. The goal was to bet…

This study looked at 77 adults with a specific type of knee fracture (Schatzker IV) to see if MRI and CT scans could predict which fractures also involve a dislocation. Researchers compared imaging features between those with and without dislocation. The goal was to help surgeons…

This study tested whether custom carbon fiber braces can reduce harmful forces on the ankle joint after a fracture, which may lower the risk of developing arthritis. Twenty-two adults with healed ankle fractures walked with and without different brace designs while researchers me…

This study tested whether crutches that give feedback to patients help them follow doctor's orders about how much weight to put on their healing leg. Twenty people with certain types of leg fractures used either regular crutches or smart crutches that tracked their weight-bearing…

This study looked at 56 patients who had surgery for a severe type of ankle fracture called a pilon fracture. Researchers compared how well patients under 40 healed versus those over 40. The goal was to see if age affects bone healing, complications, and overall recovery after a …

This study tested a new 'Mobility Toolkit' to see how well it measures walking recovery in 244 adults aged 18-60 who had surgery for serious leg fractures. Participants used the toolkit during clinic visits over a year. The goal was to see if the toolkit is easy to use and accura…