Thoracic aortic aneurysm
MONDO:0005396An aneurysm formed in the wall of the proximal portion of the descending aorta proceeding from the arch of the aorta.
83 clinical trials for this condition and its sub-types, 76 tagged with Thoracic aortic aneurysm itself.
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Stent graft aims to fix aortic arch without open surgery
Disease control Not yet recruitingThis study tracks the safety and effectiveness of a stent graft device used to treat aneurysms, dissections, or trauma in the aortic arch (the curved part of the main artery from the heart). Researchers will follow 75 patients in Japan who receive the device, monitoring for compl…
Sponsor: W.L.Gore & Associates • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Can aspirin prevent strokes after major aortic surgery? new trial aims to find out
Disease control Not yet recruitingThis study tests whether taking aspirin after a minimally invasive aortic arch repair can prevent strokes, a common complication. 224 patients will be randomly assigned to take aspirin for 3, 6, or 12 months. The researchers will track stroke rates, bleeding risks, and other outc…
Early phase 1 • Sponsor: The General Hospital of Western Theater Command • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Two sedatives, one question: can remimazolam shield the brain during aortic arch surgery?
Symptom relief Not yet recruitingAortic arch surgery temporarily cuts blood flow to the brain, which can leave patients with lasting thinking and memory problems. Researchers at Seoul National University Hospital are testing whether anesthesia with remimazolam, rather than propofol, lowers the chance of that cog…
Phase 4 • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated Sep 19, 2026 00:00 UTC
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Eye ultrasound may spot brain swelling during aortic surgery
Knowledge-focused Not yet recruitingThis study tests whether ultrasound of the optic nerve sheath, a marker of brain pressure, can track brain swelling during ascending aortic surgery. Researchers will measure the optic nerve sheath diameter before, during, and after surgery in 134 adults undergoing this procedure.…
Sponsor: Koşuyolu Kartal Heart Training and Research Hospital • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Can sound waves replace CT scans for aortic aneurysm monitoring?
Knowledge-focused Not yet recruitingThis study explores whether ultrasound can reliably measure aneurysms in the descending thoracic aorta, the part of the main artery that runs through the chest. Researchers will compare ultrasound measurements with standard CT scans in about 60 adults, including some with known a…
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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New registry tracks GORE stents in tough aortic aneurysm cases
Knowledge-focused Not yet recruitingThis registry will follow 400 people with complex aortic aneurysms who are treated with GORE devices that help keep blood flowing to vital organs. The goal is to see how well the devices work and how safe they are in everyday medical practice. Participants must need at least one …
Sponsor: W.L.Gore & Associates • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC