Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can aspirin prevent strokes after major aortic surgery? new trial aims to find out

NCT ID NCT07205250

Disease control Sponsor: The General Hospital of Western Theater Command Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking aspirin after a minimally invasive aortic arch repair can prevent strokes, a common complication. 224 patients will be randomly assigned to take aspirin for 3, 6, or 12 months. The researchers will track stroke rates, bleeding risks, and other outcomes to find the best treatment duration.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aspirin (enteric-coated tablets, 100 mg once daily)
What this could lead to
If successful, this trial could show that taking aspirin for a specific duration after aortic arch repair reduces the risk of stroke, leading to better recovery and long-term outcomes for patients.
What could go wrong
This is an early-phase trial with a small number of participants, so results may not apply to all patients. Aspirin also carries a risk of bleeding, which could be serious after surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 224 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult patients aged 18 years or older; 2. Diagnosed with type B or non-A non-B aortic dissection or thoracic aortic aneurysm according to the 2022 Chinese Expert Consensus on Stanford Type B Aortic Dissection; 3. Underwent total endovascular aortic arch repair at the participating center with concurrent intraoperative endovascular reconstruction of supra-arch branch arteries; 4. Signed the informed consent form and agreed to participate in this randomized controlled trial. Exclusion Criteria 1. Patients with known allergies to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs); 2. Patients with bleeding tendencies or active bleeding; 3. Patients who used medications affecting coagulation (e.g., warfarin, antiplatelet drugs) within 30 days before surgery; 4. Patients with a history of stroke; 5. Patients undergoing concurrent additional surgical procedures during the operation; 6. Patients with severe multi-organ dysfunction or other critical illnesses; 7. Patients unable to comply with study protocols or complete postoperative follow-up; 8. Patients participating in other drug or clinical studies that may interfere with the results of this research.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Type B or non-A non-B aortic dissection;thoracic aortic aneurysm are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

thoracic aortic aneurysm stroke disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Type B or non-A non-B aortic dissection;thoracic aortic aneurysm

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.